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Filtering by: Creator Lilley, Marvin D. Remove constraint Creator: Lilley, Marvin D. Academic Affiliation Biochemistry and Biophysics Remove constraint Academic Affiliation: Biochemistry and Biophysics

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  • Stabilization of Z-DNA by demethylation of thymine bases : a crystallization and thermo-dynamic study of d(m⁵CGUAm⁵CG)

    Creator:
    Zhou, Guangwen
    Resource Type:
    Dissertation
    Full Text:
    : a crystallization and thermo-dynamic study of d(m⁵CGUAm⁵CG) AN ABSTRACT OF THE THESIS OF Guangwen

  • Sequence conversion during adenovirus DNA replication

    Creator:
    Bennett, Kelly L.
    Abstract:
    The work in this thesis has provided conclusive genetic evidence that "panhandle" intermediates form during adenovirus replication. Adenovirus chromosomes lacking 51 by from their left -hand termini are infectious and capable of regenerating the missing origin sequence. Yet if an entire inverted terminal repeat is removed, the adenovirus chromosome is...
    Resource Type:
    Dissertation
    Full Text:
    ). (d) The intermediate structure is initially duplex only within the overlap. (e) Any heterologous

  • Nucleosome instabilities in physiological salt

    Creator:
    Yager, Thomas D.
    Abstract:
    Best scan available for figures. Some figures are high gloss photos, others are black and white photocopies.
    Resource Type:
    Dissertation
    Full Text:
    Instabilities in Physiological Salt by Thomas D. Yager A THESIS submitted to Oregon State University in

  • Base inclinations for DNA in solutions and films as revealed by linear dichroism

    Creator:
    Kang, Hunseung
    Resource Type:
    Dissertation
    Full Text:
    angles for the four individual bases. Vacuum uv flow LD demonstrates that the bases for poly[d(AC)]poly

  • Base inclinations in natural and synthetic DNAs

    Creator:
    Chou, Ping-Jung
    Abstract:
    A sophisticated computer program is developed to analyze flow linear dichroism data on nucleic acids for individual base inclinations. Measured absorption and linear dichroism data for synthetic AT and GC polymers and natural DNAs are analyzed. The reliability of the program is tested on data for the synthetic polymers, and...
    Resource Type:
    Dissertation
    Full Text:
    salt concentrations, the inclinations from perpendicular are as follows: d(A) = 16.1 ± 0.5; d(T

  • Sequence dependent conformational variations in DNA holliday junctions

    Creator:
    Hays, Franklin A.
    Abstract:
    Four-stranded DNA junctions (also known as Holliday junctions) are structural intermediates involved in a growing number of biological processes including DNA repair, genetic recombination, and viral integration. Although previous studies have focused on understanding the conformational variability and sequence-dependent formation of Holliday junctions in solution there have been relatively few...
    Resource Type:
    Dissertation
    Full Text:
    6th, 7th and 8th positions of the decanucleotide sequence d(CCnnnN6N7N8GG)) containing a series of

  • Analyses of noncanonical DNA structures

    Creator:
    Khuu, Patricia A.
    Abstract:
    The structural polymorphic nature of DNA has been long been recognized since the model of the right-handed B-DNA duplex proposed by James Watson and Francis Crick was accepted. Its malleability is thought to be critical in protein recognition and manipulation. In particular, it can form Holliday junctions, four-way DNA structural...
    Resource Type:
    Dissertation
    Full Text:
    junction (Fig. 2.1c, d) (reviewed in Lilley 1999, 2000). At low salt, the negatively charged phosphates

  • Crystal structures of DNA four-way junctions

    Creator:
    Eichman, Brandt F.
    Abstract:
    DNA four-way junctions (also known as Holliday junctions) are the primary structural intermediate during recombination, an important process responsible for biological evolution and maintenance of genomes. These junctions arise from the assembly of four nucleic acid strands to produce double-helical regions extending from a central point. Although much progress has...
    Resource Type:
    Dissertation
    Full Text:
    .................................................... 14 2.3.2 Structure solution of d(CCGGTACCGG) .................................................. 15

  • Physical studies of the yeast inner histones

    Creator:
    Mardian, James Kenneth Walker
    Abstract:
    In this work, the four yeast inner histones were prepared by the use of consecutive slab gel fractionation. The use of this technique allowed the first complete fractionation and rigorous identification of the four yeast inner histones, and made possible a study of their complexing behavior. Variants and adjuncts of...
    Resource Type:
    Dissertation
    Full Text:
    . c and d. Amino acid analyses of yeast and calf. 66 14. A non-homologous comparison of yeast H2b and

  • The analysis and prediction of DNA structure

    Creator:
    Basham, Beth E.
    Abstract:
    As genome sequencing projects begin to come to completion, the challenge becomes one of determining how to understand the information contained within the DNA. DNA is a polymorphic macromolecule; the A- B- and Z-DNA conformations have been observed by a variety of physical techniques. The magnitude of the energetic differences...
    Resource Type:
    Dissertation
    Full Text:
    of d(CGCGCG). Dr. Gary P. Schroth assisted in the design of the circular dichroism experiments