Index Catalog // ScholarsArchive@OSU

The study of pharmacokinetics in a clinical environment

Creator:: Tse, Sunny
Abstract:: This dissertation presents a research series demonstrating the use of pharmacokinetic modeling and simulations as tools to assess drug concentration and disposition in patient populations. For drugs requiring therapeutic drug monitoring, these tools are necessary to ensure patients are receiving a safe and effective dose of medication to address their...
Resource Type:: Dissertation
Full Text:: . Abstract approved: James W. Ayres This dissertation presents a research series

Chelating agents in the drug dosage design of iron preparations

Creator:: Ghannam, Musa
Abstract:: The role of iron in the body is well known for it is a component of hemoglobin, myoglobin, cytochrome, enzyme catalase and peroxidase. Iron deficiency anemia is widespread among vulnerable groups in industrialized societies and in the general population of tropical developing areas. In the United States there are ten...
Resource Type:: Masters Thesis
Full Text:: , Redacted for Privacy / Dr. James R. Ayre'V Abstract approved: The role of iron in the body is well known

Prolonged duration of action of dyphylline through prodrugs

Creator:: Panomvana, Duangchit
Resource Type:: Dissertation
Full Text:: . Redacted for privacyAbstract approved: ?'Dr. James W. Ayres A series of four diesJrs and four monoesters

Development and evaluation of a sustained release amoxicillin dosage form

Creator:: Ge, Yan, 1962-
Resource Type:: Masters Thesis
Full Text:: . James W. Ayres. Who was the instructor of my first class I took in the US. That class gave me the

Calcium alginate gels in oral dosage form design

Creator:: Lin, Shun Yih
Abstract:: In vivo research following ingesting of commercially available Lactobacillus tablets, which contain about 2X10⁶ cfu/tablet of Lactobacillus acidophilus and Lactobacillus bulgaricus cells in a dose of four tablets daily, showed serum lipoprotein concentrations did not change significantly. In order to increase the number of viable Lactobacillus bacteria after challenging in...
Resource Type:: Dissertation
Full Text:: for Privacy James W. Ayres, Ph.D. In vivo research following ingesting of commercially available

Pharmacokinetics of dyphylline after administration of prodrugs in rabbits and pigs

Creator:: Huang, Hua-pin
Abstract:: Dyphylline is an analogue of theophylline and the latter is the most popular member of the methyixanthine family in use for the treatment of asthma. Although dyphylline is devoid of some problems associated with theophylline, a reported short half-life for dyphylline (2.1 hours) has made its clinical usefulness limited. In...
Resource Type:: Dissertation
Full Text:: curves following 10 grams (23.67 m moles) of oral dipivaloyl dyphylline suspensions in pigs 94 9 Percent

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:: Farid, Samar Farghali
Abstract:: This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...
Resource Type:: Dissertation
Full Text:: Hypertensive Patients. Abstract Approved: James W This thesis describes in vitro and in vivo evaluation of a

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Creator:: Chou, Joyce Tian-wei
Resource Type:: Dissertation
Full Text:: materialized. The enthusiasm and optimism of my advisor, Dr. James Ayres, who makes this research an

Development and in vivo testing of a gastric retention device (GRD) in dogs

Creator:: Kapsi, Shivakumar G.
Abstract:: This thesis describes 1) development of a gastric retention device (GRD) to increase gastric retention time of certain drugs, 2) product formulations of an immediate release itraconazole and controlled-release ketoprofen. GRD was fabricated from crosslinked carbohydrate polymers. Rate and extent of hydration of the film in water and in simulated...
Resource Type:: Dissertation
Full Text:: received from my Prof. James W. Ayres during my graduate studies. I consider myself privileged to have

Development and evaluation of an oral controlled release and a transdermal delivery system, for melatonin in human subjects

Creator:: Lee, Beom-jin
Resource Type:: Dissertation
Full Text:: System for Melatonin in Human Sublects. Abstract approved: James W. Ayres, Melatonin (MT

ScholarsArchive@OSU

The study of pharmacokinetics in a clinical environment

Chelating agents in the drug dosage design of iron preparations

Prolonged duration of action of dyphylline through prodrugs

Development and evaluation of a sustained release amoxicillin dosage form

Calcium alginate gels in oral dosage form design

Pharmacokinetics of dyphylline after administration of prodrugs in rabbits and pigs

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Development and in vivo testing of a gastric retention device (GRD) in dogs

Development and evaluation of an oral controlled release and a transdermal delivery system, for melatonin in human subjects

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