Index Catalog // ScholarsArchive@OSU

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Brian L. Marguez for the degree of

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: acid production in macrophytic marine algae AN ABSTRACT OF THE THESIS OF Mitchell L. Wise for the

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Creator:: Jiang, Zhi-dong
Resource Type:: Dissertation
Full Text:: cyclo-ID-PHE-D-LEU-L-ILE-D- allo-ILE-L-LEU-GLY-D-BAOA-L-HSER-DHHA-L-HYPRO-L-HSERI structure. Novel

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: , 2493-2497. (b) Moore, B. M., II; Seaman, F. C.; Wheelhouse, R. T.; Hurley, L. H. J. Am. Chem. Soc. 1998

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Creator:: Sitachitta, Namthip
Abstract:: The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
Resource Type:: Dissertation
Full Text:: collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:: Milligan, Kenneth Edward
Abstract:: This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
Resource Type:: Dissertation
Full Text:: ] October 27, 1998. 29 Panda, D.; Himes, R.H.; Moore, R.E.; Wilson, L.;Jordan, M.A. Biochemistry 1997, 36

Bioactive natural products from marine algae

Creator:: Tan, Lik Tong
Abstract:: This thesis is an account of my investigation on the natural products deriving from various marine algae and has resulted in the discovery of thirteen novel bioactive metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D...
Resource Type:: Dissertation
Full Text:: extract of another collection of L. majuscula Gomont from Papua New Guinea was a prolific source of

Novel bioactive secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Creator:: Wu, Min, 1963-
Abstract:: Marine algae have been recognized as a rich resource of new and unusual organic molecules with diverse biological properties. The current need to develop new antifungal, anticancer, antibiotic and antiviral drugs has led to an intense research effort into the discovery, isolation and structure determination of potential medicinal agents from...
Resource Type:: Masters Thesis
Full Text:: , malyngamide J and malyngamide L. The structures of these new compounds, including stereochemistry, were

Biosynthetic investigations of two secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Creator:: Rossi, James V.
Abstract:: Marine cyanobacteria have been shown to produce a variety of biologically active and stucturally diverse secondary metabolites. These compounds are of interest to natural products researchers mainly because of their potential application as biomedicinals, biochemical probes, and agrichemicals. The metabolic pathways utilized by the cyanobacterium Lyngbya majuscula to generate curacin...
Resource Type:: Masters Thesis
Full Text:: of L. majuscula. Interest in the bioactive profile of curacin A prompted a pilot scale up of the

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

Creator:: Yoo, Hye-Dong
Abstract:: My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated...
Resource Type:: Dissertation
Full Text:: examined. Investigations of another Curacao collection of L. majuscula revealed a new cytotoxic

ScholarsArchive@OSU

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Bioactive natural products from marine algae

Novel bioactive secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Biosynthetic investigations of two secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

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