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Filtering by: Subject Calcium Committee Member Wilcox, Anthony

The effect of a calcium channel blocker on exercise induced muscle damage and hemodynamic parameters in young, healthy adults

Creator:

Dvorak, Roman

Abstract:

Calcium channel blockers (CCB) was studied extensively in cardiology for their tissue protective effect following myocardial infarction; we hypothesized that administration of a CCB would interfere with the processes that result in exercise-induced muscle damage (EIMD) and delayed onset muscle soreness. To investigate the effects of a CCB on a...

Resource Type:

Dissertation

Full Text:

The Effect of a Calcium Channel Blocker on Exercise Induced
Effect of the calpain inhibitor E-64-d on the degradation of α-fodrin in damaged muscle

Creator:

Boyd, Jeffrey

Abstract:

We hypothesized that calpain activity is elevated in response to muscle damage. To test this hypothesis, we examined the degradation of α-fodrin into its 150 and 145 kDa fragments following either 20 eccentric or isometric contractions. In addition, experiments were performed in the presence or absence of E-64-d, a calpain...

Resource Type:

Masters Thesis

Full Text:

cell. This is believed to be related to an increase in resting intracellular calcium levels within