The RNA genome of tobacco etch virus (TEV), a plant potyvirus, functions as an mRNA for synthesis of a
346-kilodalton polyprotein that undergoes extensive proteolytic processing. The RNA lacks a normal 5' cap
structure at its terminus, which suggests that the mechanism of translational initiation differs from that of a...
The virus-encoded proteins of tobacco etch virus (TEV), a plant potyvirus, arise by proteolytic processing of
a large polyprotein precursor. The TEV genome codes for two proteinases, a 49-kilodalton proteinase and
helper component proteinase (HC-Pro), which cleave the polyprotein at specific sites. The only known cleavage
event catalyzed by HC-Pro...