The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic
pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male
mice. A dose-dependent reduction of PC levels and activity occurred in animals given a
single intraperitoneal dose of TCDD in a corn oil carrier. The dose ranged from 1 to...
It was hypothesized that alterations in plasma concentrations of
corticosterone (CS) and prolactin (PRL) may be at least partially responsible
for polychlorinated biphenyl (PCB)-induced immunosuppression.
A 2 by 2 factorial experiment examined the interactions of PCB and P815,
an allogeneic tumor, on plasma concentrations of CS and PRL, and on...
Mouse embryo cells cultured in vitro in serum-supplemented media undergo growth
crisis, resulting in the loss of genomically normal cells prior to the appearance of
established, aneuploid cell lines. I used the technique of serum-free cell culture to develop
a serum-free mouse embryo (SFME) cell line in which serum was...