Index Catalog // ScholarsArchive@OSU

Genome scale transcriptome analysis and development of reporter systems for studying shoot organogenesis in poplar

Creator:: Bao, Yanghuan
Abstract:: Vegetative propagation allows the amplification of selected genotypes for research, breeding, and commercial planting. However, efficient in vitro regeneration and genetic transformation remains a major obstacle to research and commercial application in many plant species. Our aims are to improve knowledge of gene regulatory circuits important to meristem organization, and...
Resource Type:: Masters Thesis

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Creator:: Courter, Lauren A.
Abstract:: Human exposure to the carcinogenic polycyclic aromatic hydrocarbons (PAHs) benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) is through environmental complex mixtures, such as urban dust particulate matter (UDPM) and diesel exhaust (DE), however the potency of these PAH within a mixture is not established. To determine the effect of these mixtures on...
Resource Type:: Dissertation
Full Text:: abundance from my God. CONTRIBUTION OF AUTHORS Dr. William M. Baird provided guidance, advice and

Precursors for mitochondrial DNA replication : metabolic sources and relations to mutagenesis and human diseases

Creator:: Song, Shiwei
Abstract:: It is well known that the mitochondrial genome has a much higher spontaneous mutation rate than the nuclear genome. mtDNA mutations have been identified in association with many diseases and aging. mtDNA replication continues throughout the cell cycle, even in post-mitotic cells. Therefore, a constant supply of nucleotides is required...
Resource Type:: Dissertation
Full Text:: , William M. Baird, Michael I. Schimerlik, and Bruce E. Coblentz for taking time with this thesis. I would

Critical windows of transplacental carcinogenesis : identifying efficacious approaches to chemoprevention with dietary phytochemicals

Creator:: Castro, David J.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a re-emerging class of environmental pollutants. The persistent nature of these highly toxic compounds along with their ubiquity in the environment creates an unavoidable route of exposure. The developing fetus and neonate are a particularly susceptible population due to their incomplete complement of xenobiotic metabolizing...
Resource Type:: Dissertation
Full Text:: in chapter 3. Drs. William M. Baird and Sharon K. Krueger assisted in the manuscript preparation of

Measuring in situ biotransformation in BTEX-contaminated groundwater

Creator:: Alumbaugh, Robert E.
Abstract:: Benzylsuccinate (BSA), methylbenzylsuccinate (methylBSA), and ethylbenzylsuccinate (ethylBSA) are unambiguous anaerobic biotransformation products from toluene, xylenes, and ethylbenzene decay, respectively, and may be used to indicate intrinsic bioremediation is occurring at hydrocarbon-contaminated sites. In order to improve upon current methods that detect and quantify anaerobic hydrocarbon metabolites in field samples, solid-phase-extraction...
Resource Type:: Masters Thesis
Full Text:: chromatography advice and for being a strong advocate, and Dr. William Baird for his continuous encouragement and

Determination of fluorochemicals in waste-dominated aqueous systems

Creator:: Huset, Carin A.
Abstract:: While fluorochemicals have been detected all over the world and in wastewater treatment plants, the effect of wastewater effluent on the receiving waters has not been evaluated. In the first study, the mass flow of fluorochemicals emanating from wastewater treatment plants along the Glatt River in Switzerland was evaluated. The...
Resource Type:: Dissertation
Full Text:: would like to thank my graduate committee, Drs. William Baird, Douglas Barofsky, Jennifer Field

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Creator:: Shenvi, Swapna V.
Abstract:: Glutathione (GSH) is the predominant low molecular weight thiol antioxidant in liver tissue. GSH plays an important role in maintaining the intracellular thiol redox ratio as well as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P ≤ 0.05) in hepatocellular GSH levels. Using young (2-4...
Resource Type:: Dissertation
Full Text:: like to thank my graduate committee members, Drs. William Baird, Balz Frei, Jeffrey Greenwood, and

Regulation of mouse ribonucleotide reductase by allosteric effector-substrate interplay and hypoxia

Creator:: Chimploy, Korakod
Abstract:: In order to maintain genetic stability in eukaryotes, tight regulation of the relative sizes of deoxyribonucleoside triphosphate (dNTP) levels inside the cell is essential for optimal fidelity of DNA replication. Ribonucleotide reductase (RNR) is the enzyme responsible for proportional production of DNA precursors. Studies on regulation of this enzyme, the...
Resource Type:: Dissertation
Full Text:: committee members, Drs. Walt Ream, Lyle R. Brown, William Baird, and Linda Blythe for their support and

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Creator:: Bravo, Claudia F.
Abstract:: During the past 30 years, numerous studies have focused on the toxicities of polycyclic aromatic hydrocarbons (PAH). Laboratory and field studies have helped elucidate the detrimental effects of these chemicals on growth, reproduction and immune response. Polycyclic aromatic hydrocarbons are in the priority list of chemicals to be studied by...
Resource Type:: Dissertation
Full Text:: ): Lawrence Curtis, Mary Arkoosh, William Baird, Nancy Kerkvliet, Gary DeLander and Tracy Collier for taking

Trans-Pacific and regional atmospheric transport of anthropogenic semivolatile organic compounds in the western U.S.

Creator:: Primbs, Toby
Abstract:: The atmospheric transport of anthropogenic semivolatile organic compounds (SOCs) from Asian sources to the Western U.S. was investigated. In addition, the SOC extraction method was optimized. Hansen solubility parameter plots were used to aid in the pressurized liquid extraction (PLE) solvent selection of air sampling media in order to minimize...
Resource Type:: Dissertation
Full Text:: Westall, Jennifer Field, and William Baird) for their investment of time and support over the years to

ScholarsArchive@OSU

Genome scale transcriptome analysis and development of reporter systems for studying shoot organogenesis in poplar

Environmental complex mixtures modify benzo[a]pyrene and dibenzo[a,l]pyrene-induced carcinogenesis

Precursors for mitochondrial DNA replication : metabolic sources and relations to mutagenesis and human diseases

Critical windows of transplacental carcinogenesis : identifying efficacious approaches to chemoprevention with dietary phytochemicals

Measuring in situ biotransformation in BTEX-contaminated groundwater

Determination of fluorochemicals in waste-dominated aqueous systems

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Regulation of mouse ribonucleotide reductase by allosteric effector-substrate interplay and hypoxia

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Trans-Pacific and regional atmospheric transport of anthropogenic semivolatile organic compounds in the western U.S.

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