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Filtering by: Creator Kleywegt, Gerard J. Remove constraint Creator: Kleywegt, Gerard J. Decade 2000-2009 Remove constraint Decade: 2000-2009

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  • Quantification and reactivity of cellulose reducing ends : implication for cellulose

    Creator:
    Kongruang, Sasithorn
    Abstract:
    The primary purpose of this study was to (1) develop methods for the analysis of and (2) provide information on the chemical nature of reducing ends in typical cellulose substrates used for the study of cellulolytic enzymes. The studies were designed such that values obtained for cellulose substrates were compared...
    Resource Type:
    Dissertation
    Full Text:
    appreciation to Dr. Rosalyn Upson, Dr. John P. Bolte and Dr. John J. Garland as committee members. I am proud

  • Sequence dependent conformational variations in DNA holliday junctions

    Creator:
    Hays, Franklin A.
    Abstract:
    Four-stranded DNA junctions (also known as Holliday junctions) are structural intermediates involved in a growing number of biological processes including DNA repair, genetic recombination, and viral integration. Although previous studies have focused on understanding the conformational variability and sequence-dependent formation of Holliday junctions in solution there have been relatively few...
    Resource Type:
    Dissertation
    Full Text:
    role in the subsequent structure solution and refinement. Zebulon J. R. Jones provided some assistance

  • Crystallographic studies of Pyrenophora tritici-repentis ToxA

    Creator:
    Sarma, Ganapathy N.
    Abstract:
    Tan spot of wheat is an economically significant disease caused by the fungal pathogen, Pyrenophora tritici-repentis. Certain races of the fungus secrete Ptr ToxA (ToxA), a 13.2 kDa proteinaceous host-selective toxin that is responsible and sufficient to cause disease in susceptible wheat varieties. Disease symptoms develop only when the ToxA...
    Resource Type:
    Dissertation
    Full Text:
    -wheat interaction. Phytopathology 89, 444-449. 16 6. De Wolf, E. D., Effertz, R. J., Au, S. & Franci

  • Preparation and modification of cellooligosaccharides

    Creator:
    Akpinar, Ozlem
    Abstract:
    Cellooligosaccharides are the reaction intermediates produced during the hydrolysis of cellulose to glucose. Hence, they have the same chemical structure as cellulose, just shorter chain lengths. Cellooligosaccharides up to DP eight are soluble in water. The soluble cellooligosaccharides can be used "as is" in the food industry as non-digestible oligosaccharides...
    Resource Type:
    Dissertation
    Full Text:
    . Michael H. Penner, for his time and support throughout my study. I owe special thanks to Dr. Robert J

  • Modeling protein structure at atomic resolution

    Creator:
    Berkholz, Donald S.
    Abstract:
    This thesis includes three studies involving different aspects of modeling protein structure. The first study illustrates the levels of insight available from atomic-resolution protein structures. The second study derives general trends of protein geometry from atomic-resolution structures and shows their implications for modeling. The third study creates a model of...
    Resource Type:
    Dissertation
    Full Text:
    glutathione reductase near 1 A resolution. J. Mol. Biol. 382, 371-384. Bradley, P., Misura, K.M.S., and

  • The effect of cytosine methylation on DNA structure

    Creator:
    Vargason, Jeffrey M.
    Abstract:
    DNA methylation is common in prokaryotes and eukaryotes and has been implicated in various biological roles including gene silencing, X-chromosome inactivation, and genomic imprinting. 5-methylcytosine the "fifth base" of the genetic code comprises 1-3% of the human genome and is primarily found on cytosines within the context of the CpG...
    Resource Type:
    Dissertation

  • Learning based methods applied to the MAV control problem

    Creator:
    Salichon, Max
    Abstract:
    This thesis addresses Micro Aerial Vehicle (MAV) control by leveraging learning based techniques to improve robustness of the control system. Applying classical control methods to MAVs is a difficult process due to the complexity of the control laws with fast and highly non-linear dynamics. These methods are mostly based on...
    Resource Type:
    Dissertation

  • Applying hierarchical and adaptive control to coordinating simple robots

    Creator:
    Knudson, Matthew D.
    Abstract:
    Coordinating multiple robots to achieve a complex task requires solving two distinct control problems: the high-level control problem of ensuring that each robot aims to perform a useful task (e.g., coordination) and the low-level control problem of ensuring that each robot actually performs the correct actions to achieve its task...
    Resource Type:
    Masters Thesis

  • Navigation and coordination of autonomous mobile robots with limited resources

    Creator:
    Knudson, Matthew D.
    Abstract:
    The use of autonomous robots in complex exploration tasks is rapidly increasing. Indeed, robots can provide speed and cost effectiveness in many tasks, as well as allow operation in environments that are hostile to humans. In this dissertation we: 1) provide two adaptive navigation algorithms; 2) develop a coordination mechanism;...
    Resource Type:
    Dissertation