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Creator:: DuBois, Barent Nathan
Abstract:: Perinatal growth restriction programs higher risk for chronic disease during adulthood via morphological and physiological changes in organ systems. Perinatal growth restriction is highly correlated with a decreased nephron number, altered renal function and subsequent hypertension. I hypothesize that such renal maladaptations result in altered pharmacologic patterns for life. Pregnant...
Resource Type:: Dissertation
Full Text:: : _______________________________________ Ganesh Cherala Perinatal growth restriction programs higher risk for chronic

Creator:: Nguyen, Paulina M.
Abstract:: Studies have established that there is a greater risk for onset of adult metabolic syndrome disease such as diabetes mellitus, hypertension, hyperlipidemia, and obesity in subjects born with low birth weight (LBW). Undernourished fetuses make adaptions that result in structurally, morphologically, and functionally altered organs. In terms of drug pharmacokinetics,...
Resource Type:: Honors College Thesis
Full Text:: : ________________________________________________________________________ Mentor, Ganesh Cherala, representing Pharmacy

Creator:: Alnakhli, Ali
Abstract:: Many studies in recent literature have shown a significant link between the abnormalities of a newly born individual and the type of environment that their mothers encountered during pregnancy. More specifically, over the last two decades, a discipline of research commonly known as “fetal programming” has linked abnormalities at birth...
Resource Type:: Undergraduate Thesis and Presentation

ScholarsArchive@OSU