A two-part study was conducted to investigate some of the nutritional
relationships between dietary tri-o-cresylphosphate (TOCP), a
toxic stress material, and dietary vitamin E and selenium. In part
one, growth rate of male weanling Long-Evans rats and day-old
Japanese quail (Coturnix coturnix japonica) was used to determine the
protective action...
The objective of this research project was to evaluate the toxicity of
local pyrrolizidine alkaloid containing plants and to examine the influence
of dietary protein, with particular reference to the amino acid cysteine,
upon this toxicity.
Senecio vulgaris (common groundsel) was shown to be more toxic than
Senecio jacobaea (tansy...
Byproducts of bamboo processing, such as leaves and branches, may have potential as a livestock feedstuff. The objectives of this study were to evaluate seasonal changes in proximate composition of several bamboo species and reed canarygrass, and subsequently determine the digestibility of bamboo in ponies. Monthly samples of Phyllostachys bissetii,...
Senecio jacobaea (tansy ragwort) is a poisonous plant responsible
for livestock deaths in the Pacific Northwest. Horses and cattle are
susceptible, while sheep are resistant to the toxic action of the
pyrrolizidine alkaloids which the plant contains. Hepatic enzymes
are responsible for the biotransformation of pyrrolizidine alkaloids
into tissue damaging...
The metabolism of pyrrolizidine alkaloids and other
drugs was studied with regard to nutritional status and
species differences. Pyrrolizidine alkaloids which are biotransformed
to severely toxic metabolites were isolated
from tansy ragwort (Senecio jacobaea). Semi-purified alkaloid
crystals containing five alkaloids (senecionine, seneciophylline,
jacobine, jacoline, and jacozine) were prepared
and found...
Several experiments were conducted to examine the toxicity of Senecio jacobaea (SJ) in animals resistant to pyrrolizidine alkaloid (PA) intoxication and to determine the extent of alterations in mineral metabolism as a result of SJ intoxication. Inclusion of SJ into diets containing added copper (Cu) resulted in increased (P<.01) liver...
An extensive literature review into the causes and
controls of diarrhea was followed by three weanling rabbit
performance trials to examine the influence of dietary
modifications on diarrhea in the rabbit.
In the first set of experiments, the ion exchangers
clinoptilolite (0, 1.5 and 3.0%) and sodium bentonite (0 and...