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Filtering by: Subject Sulphur -- Metabolism -- Genetic aspects Degree Field Biochemistry and Biophysics

SLC23A1, the gene encoding sodium-dependent vitamin C transport protein 1 (SVCT1) : regulation of transcription and its functional consequences

Creator:

Michels, Alexander Johannes

Abstract:

Vitamin C is an essential component of the human diet. Uptake of vitamin C in the cell is regulated by the function of sodium-dependent vitamin C transporters (SVCTs). SVCT1 (encoded by the SLC23A1 gene) is expressed in the colon, liver and kidney, where it plays a vital role in determining...

Resource Type:

Dissertation

Full Text:

genetic regulation. We isolated a 1239-base-pair fragment of the SLC23A1 5’-flanking sequence from