A study of the relative rates of the alkyl hydrogen abstraction
from a series of meta and para substituted t-butylbenzenes by the
chlorine atom at 70°C has been carried out. Application of the
Hammett equation yielded a ρ value of -0.44 for the para compounds.
Possible explanations for the non-linearity...
Heavy alcohol consumption reduces peak bone mass in growing rodents and can lead to bone loss in both adult rats and humans. In contrast, moderate alcohol consumption appears to have a bone sparing effect in post-menopausal women. Alcohol has been reported to increase aromatase activity and influence estrogen receptor (ER)...
The unique reaction between 4, 6-dimethoxy-5-nitropyrimidine
and methylhydrazine was investigated. The reaction product was
identified as 4-hydrazino-6-hydroxypyrimidine from (a) spectral
data, (b) by direct synthesis of the product via 4-chloro-6-hydroxypyrimidine
and hydrazine, and (c) by conversion of the product to
the known 4-amino-6-hydroxypyrimidine using Raney nickel. The
product was not...
The relative rates of hydrogen atom abstraction from a series of
13 homoaryl and heteroarylmethanes by t-butoxy radical were determined at 70°C. The attacking radical was photochemically generated
from di-t-butyl peroxide. A relatively small range of relative rates
(factor of seven) has been found among the compounds studied. The
relative...