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Filtering by: Creator Graham, David W. Remove constraint Creator: Graham, David W. Degree Field Computer Science Remove constraint Degree Field: Computer Science

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  • Deep Learning for Human and Biological Languages

    Creator:
    Hong, Junki
    Abstract:
    We explore the application of deep learning to the disparate fields of natural language processing and computational biology. Both the sentences uttered by humans as well as the RNA and protein sequences found within the cells of their bodies can be considered formal languages in computer science, as sets of...
    Resource Type:
    Dissertation
    Full Text:
    Human and Biological Languages Abstract approved: David Hendrix and Liang Huang We explore the

  • Interpretable Machine Learning: Applications in Biology and Genomics

    Creator:
    Danaee, Padideh
    Abstract:
    Machine learning (ML) and deep learning (DL) models impact our daily lives with applications in natural language modeling, image analysis, healthcare, genomics, and bioinformatics. The exponential growth of biological sequence data necessitates accompanying advances in computational methods. Although deep learning is highly effective for detecting and classifying biological sequences, challenges...
    Resource Type:
    Dissertation
    Full Text:
    Machine Learning: Applications in Biology and Genomics Abstract approved: David A. Hendrix Machine

  • Shape Modeling and GPU Based Image Warping

    Creator:
    Burri, David
    Abstract:
    This project addresses the problems of manually placing facial landmarks on a portrait and finding a fast way to warp the annotated image of a face. While there are many approaches to automatically find facial landmarks, most of them provide insufficient results in uncontrolled environments. Thus I introduce a method...
    Resource Type:
    Capstone Project
    Full Text:
    AN ABSTRACT OF THE PROJECT REPORT OF David Burri for the

  • Information Foraging Theory as a Unifying Foundation for Software Engineering Research : Connecting the Dots

    Creator:
    Piorkowski, David
    Abstract:
    Empirical studies have shown that programmers spend up to one-third of their time navigating through code during debugging. Although researchers have conducted empirical studies to understand programmers’ navigation difficulties and developed tools to address those difficulties, the resulting findings tend to be loosely connected to each other. To address this...
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF David Piorkowski for the degree of Doctor of Philosophy in

  • Similarity inheritance : a model of inheritance for declarative visual programming languages

    Creator:
    Djang, Rebecca W. (Rebecca Walpole)
    Abstract:
    Declarative visual programming languages (VPLs), including spreadsheets, make up a large portion of both research and commercial VPLs. Spreadsheets in particular enjoy a wide audience, including end users. Unfortunately, spreadsheets and most other declarative VPLs still suffer from some of the problems that have been solved in other languages, such...
    Resource Type:
    Dissertation
    Full Text:
    Mishra, Chris DuPuis, David Hackenyos, Dusty Reichwein, Roger Chen, Andrei Sheretov, Zach Welch, Karen

  • Position-Dependent Codon Usage Bias in the Human Transcriptome

    Creator:
    Subramanian, Kaavya
    Abstract:
    All life depends on the reliable translation of RNA to protein according to complex interactions between translation machinery and RNA sequence features. While ribosomal occupancy and codon frequencies vary across coding regions, well-established metrics for computing coding potential of RNA do not capture such positional dependence. Here, we investigate position-dependent...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ David Hendrix All life depends on the reliable translation of RNA to protein according

  • Computational Approaches for RNA Structure Prediction with Dynamic Programming and Deep Neural Networks

    Creator:
    Deng, Dezhong
    Abstract:
    Our goal is to build a system to model the RNA sequences that reveals their structural information by using efficient dynamic programming algorithms and deep learning approaches. We aim to 1) achieve linear-time for RNA secondary structure prediction based on existing minimum free energy models; 2) utilize deep neural networks...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: David A. Hendrix Our goal is to build a system to model the RNA sequences that reveals

  • New Strategies to Develop Hidden Markov Models Combining KEGG and Pfam

    Creator:
    Gupta, Sonica
    Abstract:
    Profile Hidden Markov Models utilize the information stored in a multiple sequence alignment such as its residues and conserved regions to assign probabilities at each column. This indicates areas in the sequences where similar functionality is observed. These probability weights are then combined to assign a sequence score, which is...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract approved:_____________________________________________________ Maude David Profile

  • An enhanced version of Caesar supporting 45° geometries

    Creator:
    Lanfri, Ann R.
    Abstract:
    Caesar is an interactive graphic editor that is used to generate layouts for VLSI circuits. It runs on a VAX-11 /780 under the UNIX operating system with Berkeley extensions. Caesar has a unique and simple user interface. Phled is an enhanced version of Caesar that runs on a M68000-based engineering...
    Resource Type:
    Capstone Project
    Full Text:
    in the editor's coordinate system . (See Figure 8.) When A Is erased with B, the 1--+---"lr---W

  • Machine Learning Methods for the Discovery and Analysis of MicroRNAs

    Creator:
    Bell, Jimmy D.
    Abstract:
    MicroRNAs are a highly conserved class of small endogenous RNA, about ~22nt in length, involved in post-transcriptional gene silencing and have prominent roles in disease and development. Though the process of microRNA discovery was once an arduous task, the advent of high throughput sequencing technology has resulted in novel microRNAs...
    Resource Type:
    Masters Thesis
    Full Text:
    : ______________________________________________________ David A. Hendrix MicroRNAs are a highly conserved class of small endogenous RNA, about