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Filtering by: Committee Member Fowler, John Remove constraint Committee Member: Fowler, John Degree Field Molecular and Cellular Biology Remove constraint Degree Field: Molecular and Cellular Biology

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  • Mechanisms for the interaction of environmental mycobacteria with host cells

    Creator:
    Harriff, Melanie J.
    Abstract:
    Environmental mycobacteria are important opportunistic pathogens for many hosts, including humans, cattle, and fish. Two well-studied species are Mycobacterium avium subsp. avium, a significant cause of disseminated bacterial disease in patients with AIDS, and Mycobacterium avium subsp. paratuberculosis, the cause of Johne’s disease in cattle. Many other species that are...
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    professional and personal development. Thank you also to the members of my committee, Chris Bayne, John

  • Investigating Transcriptional Control of Specialized Gene Expression in Plants

    Creator:
    Fraser, Valerie N.
    Abstract:
    Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
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    retired. To each of my committee members—Dr. John Fowler, Dr. Jeffrey Anderson, Dr. Michael Freitag

  • Comparative Transcriptomics in Stress-Induced Rice

    Creator:
    Al-Bader, Noor M.
    Abstract:
    Rice is an important crop that feeds almost half the world population. As climate change models predict floods, drought and extreme temperatures in rice production areas, the need to better understand the genetic basis of adaptation and tolerance to abiotic and biotic stresses is vital to sustain our food supply....
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    growth in computational biology, Kari Van Zee for professional advice and support and John Fowler for

  • Identification and Functional Characterization of Genes that Regulate Biomass Production, Floral Development, and Leaf Senescence in Populus Species using Genetic Engineering and Bioinformatics Tools

    Creator:
    Lu, Haiwei
    Abstract:
    This dissertation is comprised of four studies on different elements of Populus biotechnology and genomic science: 1) growth improvement by recombinant DNA (rDNA) modification of gibberellin (GA) metabolism; 2) gene editing using zinc-finger nucleases (ZFNs); 3) induction of floral sterility by RNA interference (RNAi) of AGAMOUS (AG) gene homologs; and...
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    grateful to my committee members, Amy Klocko, Molly Megraw, John Fowler, and Robert Thompson, for their

  • Investigating Protein-lipid-membrane Interactions in Plant Cells using Bimolecular Fluorescence Complementation

    Creator:
    Tao, Kai
    Abstract:
    The overall focus of this thesis is on the distribution of specific lipids and membrane proteins of the external and internal membranes of plant cells, in the context of the roles that those lipids and proteins may play in microbe-plant interactions. The work includes the development of several new tools,...
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    mentor, my friend, and my family member. I also want to thank my committee members, Xiaolin Nan, John

  • Computational Approaches for Understanding Combinatorial Gene Regulation

    Creator:
    Ansariola, Mitra
    Abstract:
    Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...
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    thank Prof. John Fowler as my teacher and committee member for his valuable guidance on the biological

  • Transcriptional networks controlled by the fatty acid regulators FAR-1 and FAR-2

    Creator:
    Bredeweg, Erin L.
    Abstract:
    Fungi are capable of growth on a wide variety of carbon sources, both living and dead. They can produce an arsenal of enzymes and transporters for harvesting sugars, polysaccharides, amino acids, lipids and micronutrients from their environments [1]. Within the nucleus of a cell, transcription factors (TF) control whether genes...
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    !and!Rigzin! Dekhang.! I!would!like!to!thank!my!committee!members,!Dr.!Barbara!Taylor,!Dr.!John

  • The Analysis of Hormone-dependent Transcription Factors and lncRNAs in Seeds by RNA Sequencing

    Creator:
    Sall, Khadidiatou
    Abstract:
    Seed dormancy is defined as the inability of viable seeds to germinate under conditionsotherwise favorable for germination. Dormancy provides a strategy for seeds to germinateat an appropriate time. Abscisic acid (ABA) is a major hormone involved in the regulationof seed dormancy. To elucidate the molecular mechanisms of dormancy, the twoexperimental...
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    would like to thank my thesis committee members: Prof. Laurent Deluc, Prof. John Fowler, Prof. Ruth

  • Dissecting the cytoskeletal interaction during cytokinesis and the role of myosin II motors on homologous chromosomes

    Creator:
    Tseng, Kuo-Fu
    Abstract:
    Prior to cell cleavage, cytokinetic proteins are recruited into the nascent actomyosin contractile ring. Interactions between spindle microtubules and the cell cortex play a critical role in this recruitment. However, direct evidence for physical interaction between microtubules and the cortex has been lacking. Here we reveal the physical connection between...
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    my committee members, John Flower, Jeffery greenwood, Dan Rockey, Arup Indra, for their expertise

  • Characterization of the response mediated by the plant disease susceptibility gene LOV1

    Creator:
    Gilbert, Brian M.
    Abstract:
    Victoria blight, caused by fungus Cochliobolus victoriae, is a disease originally described on oats and recapitulated on Arabidopsis. Victoria blight is used as a model plant disease that conforms to an inverse gene-for-gene interaction. C. victoriae virulence is dependent upon its production of victorin, a host-specific toxin that induces programmed...
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    , Drs. Lynda Ciuffetti, Ken Johnson, John Fowler, and Anthony Wilcox for their guidance throughout the