Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...
This paper explores the use of sonification, the conversion of data into sound, to convey the significance of SARS-COV-2 and its global impact. It emphasizes sonification as a valuable tool for making complex data accessible, particularly in high school education. Sonification, an interdisciplinary field, leverages the human auditory system's pattern...
This thesis consists of five chapters: a general introduction, two manuscripts, a collection of published lesson plans, and a general conclusion. The works collected herein are united by the common theme of practical applications in plant breeding. The first manuscript reports a study performed on five malting barley lines grown...
Aqueous, two-phase systems (ATPSs) may form upon mixing two solutions of independently water-soluble compounds. Many separation, purification, and extraction processes rely on ATPSs. Predicting the miscibility of solutions can accelerate and reduce the cost of the discovery of new ATPSs for these applications. Whereas previous machine learning approaches to ATPS...
This paper addresses the high model complexity and overconfident frame labeling of state-of-the-art (SOTA) action segmenters. Their complexity is typically justified by the need to sequentially refine action segmentation through multiple stages of a deep architecture. However, this multistage refinement does not take into account uncertainty of frame labeling predicted...
Ethical and training standards across counseling-related professions contain competencies related to race and ethnicity as necessary research and practice components. One such counseling-related sub-specialty is Play Therapy, which acknowledges that professionals utilizing play therapy techniques must consider racial and cultural context, trauma, and intersectionality when working with children. However, there...
Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...