Index Catalog // ScholarsArchive@OSU

Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

Creator:: Yao, Yao
Abstract:: We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Yao Yao for the

The Extraction and Analytical Profiling of Bioactive Phospho- and Sphingolipids from Commercial Whey Protein Phospholipid Concentrate

Creator:: Ferraris, Quintin M.
Abstract:: Milk is the first source of nutrition for all mammalian neonates. The complex matrix that constitutes milk has evolved to provide optimal nutrition for the newborn, for each species, respectively. Milk fat, originating in mammary epithelial, forms lipid droplets which are stabilized in the aqueous environment by bioactive polar lipids...
Resource Type:: Dissertation
Full Text:: chemical methods of separation to recovery polar lipids, including enzyme hydrolysis (Barry et al., 2017a

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Creator:: Shalash, Ward
Abstract:: Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...
Resource Type:: Dissertation

Growth and characterization of zinc ferrite thin films for high frequency applications

Creator:: Hu, Jiqing
Abstract:: Ferrites have been used for various high frequency applications as bulk materials. These applications, however, are limited to large dimension devices. In this thesis, thin film ferrites were deposited from a low temperature solution-based deposition process that is suitable for micro-scale high frequency applications. The low temperature nature of this...
Resource Type:: Dissertation

Molecular genetic analysis of fruit development in tomato (Lycopersicon esculentum, Mill.)

Creator:: Balbi, Virginia
Abstract:: Plant hormones regulate progression through the different phases of plant development in response to endogenous and environmental cues. Gene expression studies, as well as genetic and molecular analysis of mutants with altered hormonal responses, are two common approaches to elucidate hormone response pathways. This dissertation compares ovary and fruit development...
Resource Type:: Dissertation
Full Text:: of ethylene production (Nakatsuka et al., 1998; Barry et al., 2000). The Nrtomato mutant has been

Transdermal Delivery of Atenolol to Cats

Creator:: Mohamed, Sumeia M.
Abstract:: This thesis describes in-vitro and in-vivo evaluation of a transdermal atenolol formulation developed at Oregon State University, College of Pharmacy. The formulation was prepared from carbomer as a gel base with propylene glycol, glycerol, ethanol, polysorbate 80 and dimethyl-isosorbide (DMI) as mixture of penetration enhancing agents. The effect of the...
Resource Type:: Dissertation

Systematic, genomic, and transcriptomic analysis of mycoparasitic Tolypocladium species and their Elaphomyces hosts

Creator:: Quandt, C. Alisha
Abstract:: Fungi in the genus Tolypocladium are diverse in their host associations, but the predominant ecologies include parasites of the ectomycorrhizal genus Elaphomyces and pathogens of insects. The aim of this dissertation research is to examine the evolution of these fungi and their host associations. To accomplish this several lines of...
Resource Type:: Dissertation
Full Text:: , Hiroki Sato, Bhushan Shrestha, Gi-Ho Sung, Yi-Jian Yao, and Rasoul Zare had expertise for particular

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Creator:: Otto, Shauna C.
Abstract:: Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Resource Type:: Dissertation

Oceanographic conditions around the Galápagos Archipelago and their influence on cetacean community structure

Creator:: Palacios, Daniel Mauricio
Abstract:: The objectives of this dissertation were to describe the complex oceanographic conditions around the Galápagos Archipelago (eastern equatorial Pacific), their seasonal variability, and their effects on patterns of cetacean occurrence. The physical and ecological factors leading to a plume of high phytoplankton biomass in the wake of the Galápagos were...
Resource Type:: Dissertation
Full Text:: , and Kay Yates. The staff and fellow students with OSU's Marine Mammal Program, Very! Barry, Mark

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

Creator:: Fan, Ying
Abstract:: This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Resource Type:: Dissertation

ScholarsArchive@OSU

Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

The Extraction and Analytical Profiling of Bioactive Phospho- and Sphingolipids from Commercial Whey Protein Phospholipid Concentrate

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Growth and characterization of zinc ferrite thin films for high frequency applications

Molecular genetic analysis of fruit development in tomato (Lycopersicon esculentum, Mill.)

Transdermal Delivery of Atenolol to Cats

Systematic, genomic, and transcriptomic analysis of mycoparasitic Tolypocladium species and their Elaphomyces hosts

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Oceanographic conditions around the Galápagos Archipelago and their influence on cetacean community structure

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

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