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  • Sensory, compositional and texture profile analysis of high-pressure treated fresh renneted cheese - Queso Fresco style

    Creator:
    Sandra
    Abstract:
    A sensory method was developed to determine cheese texture by hand evaluation. Cheese sensory evaluation was conducted by panelists (n=8) on four commercial samples in duplicates. Standards, descriptors, methods of each attribute evaluation, sample size, and ballot were developed based on panelists' consensus. Fifteen total attributes, divided into five groups,...
    Resource Type:
    Masters Thesis
    Full Text:
    AN ABSTRACT OF THE THESIS OF Sandra for the degree of Master

  • Evaluation of bioluminescence as a measure of bacterial cell density in porous media

    Creator:
    Uesugi, Sandra L.
    Abstract:
    Salicylate-induced, lux gene dependent bioluminescence was measured using a cooled charge-coupled device (CCD) camera to evaluate its potential as a quantitative measurement of cell density of Pseudomonas fluorescens HK44 in porous media. The CCD camera was able to detect bioluminescence from cell densities between 1x10⁶ and 1x10⁸ cells/ml in both...
    Resource Type:
    Masters Thesis
    Full Text:
    density in porous media AN ABSTRACT OF THE THESIS OF Sandra L. Uesugi for the degree of Master of

  • Understanding Visitor Motivations for Attending Fee-based Animal Encounter Programs

    Creator:
    Huynh, Sandra
    Abstract:
    Education programs at zoos and aquariums provide opportunities for visitors to learn and garner information on animal natural history and, hopefully, conservation messaging. Fee-based programs (programs with an additional fee on top of admission prices), which are commonly employed by zoos and aquariums to foster learning opportunities for visitors, are...
    Resource Type:
    Masters Thesis
    Full Text:
    AN ABSTRACT OF THE THESIS OF Sandra

  • A Dive into the Pacific Fish Microbiome: Exploration of Antibiotics from a Unique Ecosystem

    Creator:
    Austin, Molly C.
    Abstract:
    With the rise of resistant bacterial pathogens, currently prescribed antibiotics are rendered useless. In recent years, marine natural products (MNPs) have emerged as novel sources for drug leads. The ocean is a complex environment where marine animals cohabitate with many, and sometimes harmful microorganisms and viruses, but resist infections. Developed...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Sandra Loesgen With the rise of resistant bacterial pathogens, currently prescribed

  • Bioactivity Screening and Gene Activation Strategies in Fungi

    Creator:
    Coddington, Nathan C.
    Abstract:
    Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract approved: ______________________________________________________________ Sandra Loesgen

  • Gene Expression, Structure Elucidation, and Bioactivity of Aspergillus Natural Products

    Creator:
    Neuhaus, George F.
    Abstract:
    The study of natural products (NPs) and their application has shaped humanity. Starting with the idea of using plants as medicine, it has now grown into the science of purifying and identifying organic molecules from nature to study their inherent biological activities. Understanding the molecular structures of NPs is the...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Sandra Loesgen The study of natural products (NPs) and their application has shaped

  • Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

    Creator:
    Adpressa, Donovon A.
    Abstract:
    Fungi have long been a prolific source of clinically approved drugs. The antibiotic penicillin, the cholesterol lowering statins, and the immunosuppressant cyclosporine have changed the treatment of human diseases in the last century. Recently, genome analysis of filamentous fungi has revealed that the biosynthetic potential for natural product expression is...
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________________________ Sandra Loesgen Fungi have long been a prolific source of clinically approved drugs. The

  • Isolation, Characterization, and Antibiotic Activity of Fungal Metabolites from an Algal Endophyte

    Creator:
    Stoumbos, Demetri
    Abstract:
    Pseudomonas aeruginosa is a gram-negative nosocomial pathogenic bacterium known for its resilience against antibiotics. The bacterium infects over 50,000 patients each year in the United States, with 13% of reported cases involving multi-drug-resistant strains of Pseudomonas. This research discovered several fungal natural products with promising activity against Pseudomonas aeruginosa. The...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract approved: ______________________________________________________ Sandra Loesgen

  • Bioprospecting the Chemical Diversity of Plant-associated Fungi

    Creator:
    González-Montiel, Gisela Abigail
    Abstract:
    Fungi have long been used for discovery of new chemical scaffolds. In the clinical setting, the fungal natural products penicillin, statins, and cyclosporine have revolutionized medicine to treat diseases and infections. In the environment, fungal natural products have been used as herbicides, fungicides, and insecticides to protect crops, livestock, and...
    Resource Type:
    Masters Thesis
    Full Text:
    : ______________________________________________________ Sandra Loesgen Fungi have long been used for discovery of new chemical scaffolds. In the

  • Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

    Creator:
    Kaweesa, Elizabeth Namagoba
    Abstract:
    Mensacarcin is a stereogenic complex polyketide with potent anti-tumor activity produced by a soil-dwelling Streptomyces bottropensis. The US National Cancer Institute (NCI) 60 human tumor cell line anticancer drug screen (NCI-60) reveals mensacarcin’s cytostatic properties in almost all tested cell lines and distinct cytotoxic properties specifically in eight melanoma cell...
    Resource Type:
    Masters Thesis
    Full Text:
    approved: ______________________________________________________ Sandra Loesgen Mensacarcin is a