Index Catalog // ScholarsArchive@OSU

Acute bioactivation and hepatotoxicity of ketoconazole in rat and the determinant presence of flavin-containing monooxygenase (FMO) isoforms in human duodenum, jejunum, ileum, and colon microsomes and Caco-2 cell line

Creator:: Buckholz, Cheryl J.
Abstract:: Two specific goals were addressed for this dissertation. First to investigate and identify the mechanistic profile of ketoconazole (KT)-induced hepatotoxicity by utilizing in vivo and in vitro approaches determining the mechanism of action for the hepatotoxicity incurred. To date, there has not been a mechanistic determination of the hepatotoxicity associated...
Resource Type:: Dissertation
Full Text:: Hepatotoxicity of Ketoconazole in Rat and the Determinant Presence of Flavin-containing Monooxygenase (FMO

Composition of flavonoid phenolic polymers isolated from red wine during maceration and significance of flavan-3-ols in foods pertaining to biological activity

Creator:: Aron, Patricia M.
Abstract:: Representing the most common flavonoid consumed in the American diet, the flavanols and their polymeric condensation products, the proanthocyanidins, are regarded as functional ingredients in various beverages, whole and processed foods, herbal remedies and supplements. Their presence in food affects food quality parameters including astringency, bitterness, sourness, sweetness, salivary viscosity,...
Resource Type:: Masters Thesis
Full Text:: Effect on food quality............................................................................6

Investigations of gluten proteins from functional and historical perspective

Creator:: Zhang, Ying
Abstract:: Wheat (Triticum aestivum) is one of the world’s major staple food crops, with flour produced from starchy endosperm being used for breads, cakes, noodles and various other wheat-based foods. The unique bread making properties of wheat are primarily attributed to its gluten-forming storage proteins: gliadins and glutenins. This study investigated...
Resource Type:: Masters Thesis
Full Text:: )..………………………………………………64 3.2 Two-way ANOVA results of control effect…………………………………64 3.3 Onset temperatures under

A study of the relationship of the use of various drugs to the visual-motor performance of college students

Creator:: Antone, Eugene Joseph, Jr.
Abstract:: The purpose of the study was to compare the visual-motor performance of college students who reported ingestion of certain drugs with those college students who reported no drug ingestion. The study drugs included the following drugs or groups of drugs: tobacco, alcohol, marijuana, LSD, mescaline, barbiturates, and amphetamines. A total...
Resource Type:: Dissertation
Full Text:: or psychoneuroses. Chronic Toxic Reactions: An adverse psychological or physiological reaction to

Does Caffeine Intake Impact Menstrual Function? Assessment of Caffeine Intake in Active Women with and Without Exercise Induced Menstrual Dysfunction (ExMD)

Creator:: Derringer, Andrew R., Hand, Taryn M., and Manore, Melinda M.
Abstract:: It has been hypothesized that caffeine intake can directly interfere with estrogen synthesis; it is also well documented that caffeine can increase energy expenditure. Active women with ExMD are at risk for the female athlete triad, a syndrome associated with negative energy balance, leading to menstrual dysfunction and eventually poor...
Resource Type:: Poster

Purification and characterization of recombinant calpain-5

Creator:: Wang, Mei-Chuan
Abstract:: Recombinant human calpain-5 was expressed in insect cells using a baculovirus system. The expressed calpain-5 was purified by both traditional chromatography and by affinity-column chromatography. Both methods yielded active protease. Calpain-5 displayed very limited hydrophobicity. This indicated that calpain-5 is not a membrane binding protein. Calpain-5 had pI of 8.3....
Resource Type:: Dissertation
Full Text:: cysteine proteases. Although the exact physiological roles of calpains remain to be elucidated, calpains

Estimation of the energy cost of walking 10,000 steps

Creator:: Birdsley, Kari L.
Abstract:: There is a strong campaign underway to promote increased physical activity among the U.S. population. The U.S. Surgeon General and the U.S. Dietary Guidelines have presented physical activity recommendations in terms of the amount of time accumulated in physical activity and/or in terms of energy expenditure over the course of...
Resource Type:: Masters Thesis
Full Text:: activity has a positive effect on one's physical well being. The American College of Sports Medicine

Exercise, nutrition, and homocysteine

Creator:: Joubert, Lanae Marie
Abstract:: Exercise increases B-vitamin (B6, B12, folate) dependent metabolic reactions, especially those related to energy production and the rebuilding and repairing of muscle tissue. These same B-vitamins are also important in maintaining low blood levels of homocysteine (Hcy), a cardiovascular disease (CVD) risk factor. Hcy levels rise when the metabolism of...
Resource Type:: Dissertation
Full Text:: exercise intensity is vigorous. Research examining the effect of exercise on Hcy is limited with no

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Creator:: Farley, Sherry Mae
Abstract:: The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Resource Type:: Dissertation
Full Text:: and d4-PK decreased in -T-injected rats demonstrating that vitamin E’s untoward effect on vitamin K

Impact of weak and strong acids on the destruction of lactic acid bacteria during high pressure processing

Creator:: Sarangapani, Rama Krishna
Abstract:: High hydrostatic pressure (HHP) affects the pH of weak acids due to an increased degree of acid dissociation while under pressure. The temporary pH reduction by high pressure in such a case may influence the barotolerance of microorganisms. The objective of this study was to determine the impact of weak...
Resource Type:: Masters Thesis
Full Text:: bacteria across a range of pH under high hydrostatic pressure conditions. The effect of two acid groups

ScholarsArchive@OSU

Acute bioactivation and hepatotoxicity of ketoconazole in rat and the determinant presence of flavin-containing monooxygenase (FMO) isoforms in human duodenum, jejunum, ileum, and colon microsomes and Caco-2 cell line

Composition of flavonoid phenolic polymers isolated from red wine during maceration and significance of flavan-3-ols in foods pertaining to biological activity

Investigations of gluten proteins from functional and historical perspective

A study of the relationship of the use of various drugs to the visual-motor performance of college students

Does Caffeine Intake Impact Menstrual Function? Assessment of Caffeine Intake in Active Women with and Without Exercise Induced Menstrual Dysfunction (ExMD)

Purification and characterization of recombinant calpain-5

Estimation of the energy cost of walking 10,000 steps

Exercise, nutrition, and homocysteine

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Impact of weak and strong acids on the destruction of lactic acid bacteria during high pressure processing

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