Search Constraints

Start Over
Filtering by: Creator Heath, Simon Remove constraint Creator: Heath, Simon Subject Transcription factors Remove constraint Subject: Transcription factors

Search Results

  • Effects of nucleosomes on transcription by polymerase I in a reconstituted system

    Creator:
    Georgel, Philippe, 1961-
    Abstract:
    The aim of this study was to gain more information about the interactions between DNA and the histone octamer during the process of transcription. This work used a pUC8 plasmid derivative that contained the core promoter region of the RNA polymerase I of Acanthamoeba castellanii, placed upstream of four repeats...
    Resource Type:
    Dissertation
    Full Text:
    , on a hydroxylapatite column equilibrated with the same buffer, to remove the DNA (Simon and

  • The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

    Creator:
    Kyrylkova, Kateryna
    Abstract:
    BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
    Resource Type:
    Dissertation
    Full Text:
    Desmoplakin in Bcl11b-/- mice rescues impaired neurogenesis (Simon et al., 2012). The vomeronasal organ is

  • Roles of homeodomain transcription factors during organogenesis

    Creator:
    Xu, Jun
    Abstract:
    The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
    Resource Type:
    Dissertation

  • Transcriptional networks controlled by the fatty acid regulators FAR-1 and FAR-2

    Creator:
    Bredeweg, Erin L.
    Abstract:
    Fungi are capable of growth on a wide variety of carbon sources, both living and dead. They can produce an arsenal of enzymes and transporters for harvesting sugars, polysaccharides, amino acids, lipids and micronutrients from their environments [1]. Within the nucleus of a cell, transcription factors (TF) control whether genes...
    Resource Type:
    Dissertation