Hop downy mildew (DM) is an obligate parasite causing severe losses in hop if not controlled. Resistance to this pathogen is a primary goal for hop breeding programs. The objective of this study was to identify QTLs linked to DM resistance. Next-generation-sequencing was performed on a mapping population segregating for...
Evolution of the mobile communication standards and proliferation of hand-held devices mandate stringent Analog-to-Digital Converter (ADC) specifications. Among various ADCs, a ∆Σ ADC is best known as a power-efficient ADC when more than 12b is required. However, a conventional discrete-time (DT) ∆Σ Modulator (∆ΣM) is inadequate for low-power wideband applications...
Pharmacokinetics (PK) is the study of the transit of drug into, within and removal from the body to reveal how the body acts on a drug when it is taken. There are four major areas in PK: absorption, distribution, metabolism and elimination. Pharmacokinetics research can be separated into two areas:...
The abilities of plant biologists to characterize the genetic basis of physiological traits are limited by their abilities to obtain quantitative data representing precise details of trait variation and mainly to collect this data on a high-throughput scale at low cost. Deep learning-based methods have demonstrated unprecedented potential to automate...
Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...
We review and synthesize the geologic record that
constrains the sources of sea level rise and freshwater discharge
to the global oceans associated with retreat of ice
sheets during the last deglaciation. The Last Glacial Maximum
(~26–19 ka) was terminated by a rapid 5–10 m sea
level rise at 19.0–19.5...
Hydrocarbon solvents are widely used in the production of paints, adhesives, dyes, polymers, plastics, textiles, printing inks, agricultural products and pharmaceuticals. While the neuropathic potential of aliphatic solvents was shown in the 1970s, little is known about the neuropathic potential of aromatic solvents. The present study examines such solvents, 1,2-diethylbenzene...
L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in
many organisms, including primates, as an intermediate in lysine degradation. The
pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate
oxidase (L-PO), and appears to be tissue specific to the central nervous system...