In this study, we characterize the behavioral response of larval zebrafish (Danio rerio) to the noxious chemical allyl isothiocyanate (AITC), an agonist of the nociceptive TRPA1 ion channel, and utilize AITC as an aversive stimulus in an associative learning paradigm. We find that larvae exposed to AITC in both a...
Background. As part of the nationwide student completion agenda, the Achieving the Dream (ATD) national reform network was established to help community colleges quickly institute sustainable change scaled to impact all students at the institution in a short period of time. Although ATD has been in existence for over a...
Slow magnetosonic shock fronts are unstable to changes made to their shape, a phenomenon known as corrugation instability. The computational models studied considers a system where plasma travels across a shock front. Using the code Linogen, the corrugation instability of a shock front can be theoretically modeled. The results show...
The effect of heterozygosity on the phenotypic stabilities of six
morphological plant characteristics was studied in hybrid crosses of
two self-pollinated barley species Hordeum vulgare L., emend Lam.
and Hordeum distichum L., emend Lam. Experimental material
consisting of parents and their F₁ diallel progeny were grown at two
field locations...
This Thesis aims to determine whether we can improve the accuracy, resolution, and speed of calculations for common power system problems using simple computational models that scale well to machine learning and high performance computing solutions. The second chapter of this Thesis implements more precise aging and degradation models for...
Nuclear Thermal Rocket (NTR) designs have received renewed interest due to their superior thermal efficiencies and a rehabilitated desire for space exploration. This has resulted in improved NTR fuel designs that have unique properties that require investigation and testing in order to be more safely designed and operated.
Oak Ridge...
While robotic systems may have once been relegated to structured environments and automation style tasks, in recent years these boundaries have begun to erode. As robots begin to operate in largely unstructured environments, it becomes more difficult for them to effectively interpret their surroundings. As sensor technology improves, the amount...
Free energy is a fundamental property of a thermodynamic system, from which pressure, entropy, and other interesting properties can be derived. It is useful, then, to be able to accurately compute the free energy at various densities and temperatures in a way that can serve as the basis for further...
With the rise of resistant bacterial pathogens, currently prescribed antibiotics are rendered useless. In recent years, marine natural products (MNPs) have emerged as novel sources for drug leads. The ocean is a complex environment where marine animals cohabitate with many, and sometimes harmful microorganisms and viruses, but resist infections. Developed...
The serotonergic system plays a significant regulatory role in osteoblast differentiation and proliferation. Serotonin (five-hydroxytryptamine or 5HT) may promote or inhibit osteoblast proliferation depending upon the serotonin receptor isoforms expressed by the cell. Classically, 5HT receptor 1B (5HTR1B) reduces osteoblast proliferation by inhibiting phosphorylation of the cAMP response element binding...