Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
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Biosynthesis
Andrew Osborn
Research Mentors: Dr. Taifo Mahmud, Dr. Kerry McPhail
A Bioresource
Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
Full Text:
By
Andrew Osborn
An Undergraduate Thesis Submitted to
Oregon State University
The City of Newport, in Lincoln County, is undergoing change in response to shifts in
demographics and the economic base. Following a 1990 report, a comparative growth study of the region
was initiated to observe the effectiveness of Oregon's mandatory urban growth boundaries. Data was
collected for land use permits...
The City of Newport, in Lincoln County, is undergoing change in response to shifts in
demographics and the economic base. Following a 1990 report, a comparative growth study of the region
was initiated to observe the effectiveness of Oregon's mandatory urban growth boundaries. Data was
collected for land use permits...
The City of Newport, in Lincoln County, is undergoing change in response to shifts in
demographics and the economic base. Following a 1990 report, a comparative growth study of the region
was initiated to observe the effectiveness of Oregon's mandatory urban growth boundaries. Data was
collected for land use permits...
The City of Newport, in Lincoln County, is undergoing change in response to shifts in
demographics and the economic base. Following a 1990 report, a comparative growth study of the region
was initiated to observe the effectiveness of Oregon's mandatory urban growth boundaries. Data was
collected for land use permits...
The City of Newport, in Lincoln County, is undergoing change in response to shifts in
demographics and the economic base. Following a 1990 report, a comparative growth study of the region
was initiated to observe the effectiveness of Oregon's mandatory urban growth boundaries. Data was
collected for land use permits...
Obtaining accurate estimates of animal abundance is made difficult by the fact that most
animal species are detected imperfectly. Early attempts at building likelihood models that
account for unknown detection probability impose a simplifying assumption unrealistic for
many populations, however: no births, deaths, migration or emigration can occur in the...
Here, we describe and demonstrate a geographic information systems-based lithic morphometric research (GLiMR) software approach. GLiMR accurately and rapidly handles a sequence of ArcGIS procedures to extract geometric morphometric data from 2D and 3D scan files of lithic artifacts. GLiMR generates three main types of geometric properties: shape data, topographic...
Here, we describe and demonstrate a geographic information systems-based lithic morphometric research (GLiMR) software approach. GLiMR accurately and rapidly handles a sequence of ArcGIS procedures to extract geometric morphometric data from 2D and 3D scan files of lithic artifacts. GLiMR generates three main types of geometric properties: shape data, topographic...
