Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...
Nucleic acid therapeutics has cemented itself as one of the most efficacious and robust avenues for treatment of a wide range of diseases from vaccine development to treatment of liver, retina, cancer applications. Non-viral mediated gene delivery using lipid-based nanoparticle (LNP) carriers has proven its compatibility with addressing unexpected, fast...
The goal of this research was to explore if an inkjet 3D printing technology, known as Multi Jet Fusion (MJF), could be used to fabricate magnetic polymer nanocomposites with systematically varied volume fractions of magnetic nanoparticles. Soft magnetic nanoparticles were chosen because of their applications in communications technologies and other...