In this investigation, six different endogenous thyroid hormone derivatives—T₄, T₃, TA₄, TA₃, T₁-Amine, and N-Acetylated T₁-Amine—were tested to gain insight into their permeability coefficients and efflux ratios across a monolayer of Madin-Darby Canine Kidney (MDCK II) cells. The results indicate that T₃ and T₄ were unable to traverse the membrane...
Uveitis is a serious ophthalmological disorder characterized by intraocular infiltration of inflammatory cells. In most cases, uveitis is derived from the adaptive immune response. More specifically, CD4+ T lymphocytes play an important role in the pathogenesis of uveitis by recognizing uveitogenic antigen and orchestrating the immune response. While it is...
This study sought to explore the differences between the varied academic advising models in the College of Science at Oregon State University through the feedback of its undergraduate students and advisors. Using parallel surveys of students and their academic advisors, it found that the decentralized and centralized models each had...
Approximately five to eight percent of domestic rams demonstrate a sexual attraction
towards other rams, directing no sexual behaviors towards estrous ewes. It has been
observed that these male-oriented rams (MORs) have a greater abundance of prolactin
mRNA than female-oriented rams in the medial preoptic area of the anterior
hypothalamus...
Adolescents are faced with many life changing decisions as they prepare for adulthood. The choice to engage in sexual activity is among the most difficult of these decisions. Risks, such as unplanned pregnancy, sexually transmitted infections (STIs), and other physical complications associated with early onset sexual activity are a harsh...
Inflammation is one of the first, most important responses of the immune system when presented with infection and is mediated primarily by eicosanoids and cytokines. The goal of this research was to generate monoclonal antibodies against murine IL17C, a poorly characterized cytokine involved in inflammation and linked to inflammatory conditions....
Sickle cell disease (SCD) is a phenotypically variable disorder of hemoglobin that leads to abnormally shaped and dysfunctional red blood cells. Several studies have attempted to construct early predictive models for SCD, including Miller et al.’s (2000) model which uses easily identifiable predictors in early life. The primary aim of...