Index Catalog // ScholarsArchive@OSU

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Creator:: Mellbye, Brett L.
Abstract:: High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
Resource Type:: Honors College Thesis
Full Text:: like to acknowledge my committee members, Dr. Douglas Barofsky, Kevin Vergin, and Dr. Ulrich Stingl for

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Creator:: Kulkarni, Sandhya N.
Resource Type:: Masters Thesis
Full Text:: members, Dr. Douglas Barofsky, Dr. Mark Zabriskie and Dr. Markle Douglas. I appreciate the cooperation

Alkylation of peptides and proteins by S-(2-chloroethyl)glutathione and characterization of adducts by mass spectrometry

Creator:: Erve, John C. L.
Abstract:: Glutathione, a ubiquitous intracellular tripeptide, protects cells by reacting with electrophiles and radicals that can damage cellular macromolecules. However, glutathione conjugation is now recognized as one mechanism by which drugs and xenobiotics can also be converted to reactive intermediates having toxic consequences to cells. The halogenated alkane 1,2-dichloroethane forms S-(2-chloroethyl)...
Resource Type:: Dissertation
Full Text:: requirements, and Douglas F. Barofsky, for his instruction in the fine art of scientific writing. Elisabeth

Developmental and dietary regulation of flavin-containing monooxygenase

Creator:: Su, Shelley A. Larsen
Resource Type:: Dissertation
Full Text:: Barofsky for their assistance throughout my research. Lastly, I would like to thank my coathors, friends

Mass spectrometric analysis of bovine neurofilament proteins NF-L, NF-M, and NF-H : peptide mapping, phosphorylation and alkylation site identification

Creator:: Mixon, April E.
Abstract:: Neurofilament proteins are intermediate filaments found in the neuronal cytoskeleton. Phosphorylation of these proteins is considered important for the assembly and stability of the filaments. Accurate molecular weights have been difficult to measure, largely because the high degree of phosphorylation results in M[subscript r]'S that are significantly greater than dictated...
Resource Type:: Masters Thesis
Full Text:: support. I thank Don Griffin, Brian Arbogast and Lilo Barofsky for their excellent technical assistance

Formaldehyde-free wood adhesives from soybean protein and lignin : development and characterization

Creator:: Liu, Yuan
Abstract:: Presently, the production of wood composites relies on the formaldehyde-based wood adhesives such as phenol-formaldehyde (PF) and urea-formaldehyde (UF). However, their dependence on exhaustible fossil fuels and the emission of carcinogenic formaldehyde prompt to develop an environmentally friendly adhesive from renewable natural resources. This work focuses on development and characterization...
Resource Type:: Dissertation
Full Text:: Karchesy, Dr. Michael Peimer and Dr. Douglas Barofsky for being my committee members, and for their

Mechanisms for the interaction of environmental mycobacteria with host cells

Creator:: Harriff, Melanie J.
Abstract:: Environmental mycobacteria are important opportunistic pathogens for many hosts, including humans, cattle, and fish. Two well-studied species are Mycobacterium avium subsp. avium, a significant cause of disseminated bacterial disease in patients with AIDS, and Mycobacterium avium subsp. paratuberculosis, the cause of Johne’s disease in cattle. Many other species that are...
Resource Type:: Dissertation
Full Text:: Fowler, and Doug Barofsky, who have freely offered their time and advice. A special thanks to those

Mass spectrometric studies on peptides and proteins : conformations of Escherichia coli Thioredoxin and its alkylated adducts studied by hydrogen/deuterium exchange and HPLC-electrospray ionization mass spectrometry

Creator:: Kim, Moo-young
Abstract:: E. coli thioredoxin (TRX) was modified by the episulfonium ion derived from S-(2-chloroethyl)glutathione (CEG) or S-(2-chloroethyl)cysteine (CEC). The alkylation site was located at Cys-32, which was confirmed by tandem mass spectrometry. Two forms of native TRX, Oxi- and Red-TRX, and two modified TRXs, GS- and Cys-TRX, were examined by hydrogen/deuterium...
Resource Type:: Dissertation
Full Text:: Barofsky, and Dr. Goran Zovanovic for their willingness and critical evaluation of my thesis. I would

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:: Hanson, Eric Scott
Resource Type:: Dissertation
Full Text:: . Lastly, I thank the members of my committee, Drs. Christopher Mathews, Douglas Barofsky, Shing Ho, Jo-Ann

Automethylation : a response to enzyme aging

Creator:: Lindquist, Jonathan A.
Abstract:: This is the first study to explore the ability of an enzyme to recognize and repair spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM) is known to repair damage that arises from a spontaneous isomerization of aspartyl and asparaginyl residues in other proteins during aging. As...
Resource Type:: Dissertation
Full Text:: in the preparation of this thesis. I would like to thank my committee: Dr. Douglas Barofsky, Dr

ScholarsArchive@OSU

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Alkylation of peptides and proteins by S-(2-chloroethyl)glutathione and characterization of adducts by mass spectrometry

Developmental and dietary regulation of flavin-containing monooxygenase

Mass spectrometric analysis of bovine neurofilament proteins NF-L, NF-M, and NF-H : peptide mapping, phosphorylation and alkylation site identification

Formaldehyde-free wood adhesives from soybean protein and lignin : development and characterization

Mechanisms for the interaction of environmental mycobacteria with host cells

Mass spectrometric studies on peptides and proteins : conformations of Escherichia coli Thioredoxin and its alkylated adducts studied by hydrogen/deuterium exchange and HPLC-electrospray ionization mass spectrometry

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Automethylation : a response to enzyme aging

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