Peroxiredoxins (Prxs) were not recognized as a family of enzymes until the 1990s but are now known to be the dominant peroxidases in most organisms. Here, the history and fundamental properties of peroxiredoxins are briefly reviewed, with a special focus on describing how an exquisitely tunable balance between fully folded...
An
investigation was
made
into certain
aspects
of
protein
synthesis
at
different
developmental stages
of the
flesh fly
Sarcophaga
bullata.
This
included
measurements
of the
incorporation of
labeled
amino
acids into
protein
by intact cells
from
a
single
organ, the
larval
fat
body,
and
a
study
of
amino
acid
activating...
The first area of investigation involves the electron transport
of sub-mitochondrial particles and their components. The second
area is the synthesis of ATP and other energy linked reactions and
components of the energy conservation and transfer apparatus.
Investigations on the nature of the tetramethyl-p-phenylenediamine
(TMPD) shunt indicated that tetrachlorohydroquinone (TCHQ)...
Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...
The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
