Index Catalog // ScholarsArchive@OSU

Inhibiting the Receptor Tyrosine Kinase-like Orphan Receptor 2 (ROR2) enzymewith small molecules for the treatment of cancer

Creator:: Rodgers, Brett, Nishita, Michiru, and Bisson, William H.
Abstract:: Based on recent findings, our hypothesis is that the inhibition of the Receptor tyrosine kinase-like orphan receptor 2 (ROR2) enzyme can lead to tumor suppression. ROR2 are trans-membrane proteins that are part of the receptor tyrosine kinase (RTK) family. ROR2 is generally not expressed in most normal adult tissues and...
Resource Type:: Poster
Full Text:: novel lead compounds for multiple tumor types. Brett Rodgers1 , Michiru Nishita2, William H. Bisson1

Drug Repurposing in Chemical Genomics: Can We Learn from the Past to Improve the Future?

Creator:: Bisson, William H.
Abstract:: More needs to be done by the private sector to optimize the drug discovery and development pipeline. In addition, significant efforts should also be focused on the understanding of mechanism of diseases, on the characterization of unexplored biochemical pathways and on the validation of new protein targets. Chemical genomics, which...
Resource Type:: Article
Full Text:: Chemical Genomics: Can We Learn from the Past to Improve the Future? AUTHOR: William H. Bisson

Lives of the presidents of the United States of America : from Washington to the present time

Creator:: Abbott, John S. C. (John Stevens Cabot), 1805-1877 and Conwell, Russell Herman, 1843-1925
Abstract:: Gerald W. Williams Collection
Resource Type:: Book

In the Circuit Court of the United States for the District of Oregon, Ninth Judicial Circuit, United States of America, complainant vs. Oregon and California Railroad Company, et al., defendants : involving railroad land grants : in equity, no. 3340 : bill of complaint

Creator:: United States, United States. Circuit Court (Oregon), and Oregon and California Railroad Company
Abstract:: Gerald W. Williams Collection
Resource Type:: Book

Adventures of the first settlers on the Oregon or Columbia River, 1810-1813

Creator:: Ross, Alexander, 1783-1856
Abstract:: Gerald W. Williams Collection
Resource Type:: Book

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Creator:: Hartung, Daniel M., Bourdette, Dennis N., Ahmed, Sharia M., and Whitham, Ruth H.
Abstract:: Objective: To examine the pricing trajectories in the United States of disease-modifying therapies (DMT) for multiple sclerosis (MS) over the last 20 years and assess the influences on rising prices. Methods: We estimated the trend in annual drug costs for 9 DMTs using published drug pricing data from 1993 to...
Resource Type:: Article

Genetic diversity in coastal cutthroat trout and Dolly Varden in Prince William Sound, Alaska

Creator:: Griswold, Kitty E.
Abstract:: Genetic diversity of two salmonid species, Dolly Varden (Salvelinus malma) and coastal cutthroat trout (Oncorhynchus clarki clarki) in Prince William Sound, Alaska were examined at multiple spatial scales with three molecular markers. Pleistocene glaciers covered what is now Prince William Sound 8,000- 12,000 years ago and both species colonized the...
Resource Type:: Dissertation
Full Text:: CUTTHROAT TROUT IN PRINCE WILLIAM SOUND, ALASKA Kitty E. Griswold1, Gordon H Reeves2 'Oregon State

The mountain that was "God" ; being a little book about the great peak which the Indians named "Tacoma," but which is officially called "Rainer"

Creator:: Williams, John Harvey, 1864-
Abstract:: Second Edition revised and greatly enlarged, with 190 illustrations, including eight colored halftones.
Resource Type:: Book
Full Text:: " RAJ IER" By .JOHN H . \V l L L I A M S 0, rarest miracle of mountain heights, Thou hast the sky

Effect of β-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease

Creator:: Lee, David S. H., Markwardt, Sheila, McAvay, Gail J., Gross, Cary P., Goeres, Leah M., Han, Ling, Peduzzi, Peter, Lin, Haiqun, Dodson, John A., and Tinetti, Mary E.
Abstract:: CONTEXT: In older adults with multiple conditions, medications may not impart the same benefits seen in patients who are younger, or without multi-morbidity. Furthermore, medications given for one condition may adversely affect other outcomes. Beta-blocker (β-Blocker) use with coexisting cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) is such...
Resource Type:: Article

Model systems for structural investigations into peroxiredoxin catalysis, conformation change, and inactivation

Creator:: Perkins, Arden
Abstract:: Peroxiredoxin (Prx) enzymes catalyze the reduction of hydrogen peroxide, peroxynitrous acid, and organic peroxides, and are extremely efficient peroxidases, with k[subscript cat]/K[subscript M] on the order of 10⁷ - 10⁸ M⁻¹ s⁻¹. Besides their role in oxidative stress defense, evidence has accumulated that some eukaryotes, including humans, use Prxs as...
Resource Type:: Dissertation
Full Text:: members for your guidance in the completion of my PhD, in particular Dr. William Bisson, who allowed me

ScholarsArchive@OSU

Inhibiting the Receptor Tyrosine Kinase-like Orphan Receptor 2 (ROR2) enzymewith small molecules for the treatment of cancer

Drug Repurposing in Chemical Genomics: Can We Learn from the Past to Improve the Future?

Lives of the presidents of the United States of America : from Washington to the present time

In the Circuit Court of the United States for the District of Oregon, Ninth Judicial Circuit, United States of America, complainant vs. Oregon and California Railroad Company, et al., defendants : involving railroad land grants : in equity, no. 3340 : bill of complaint

Adventures of the first settlers on the Oregon or Columbia River, 1810-1813

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Genetic diversity in coastal cutthroat trout and Dolly Varden in Prince William Sound, Alaska

The mountain that was "God" ; being a little book about the great peak which the Indians named "Tacoma," but which is officially called "Rainer"

Effect of β-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease

Model systems for structural investigations into peroxiredoxin catalysis, conformation change, and inactivation

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