The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
This dissertation investigates the effect of endogenous and exogenous events on firm behavior and performance. These are fundamental questions in economics. The contribution of this study is threefold. First, it provides estimates of the impact of mergers on railroad efficiency, which has important antitrust implications. Second, it provides new estimates...
Many new applications of energy system devices have been developed to save energy, improve the controllability and stability of industrial processes, and reduce the weight, volume and cost of consumer devices. Due to the novelty of these devices, traditional empirical methods and lumped-parameter circuit theory methods are not sufficient for...
Chinese international students in American colleges and universities report low levels of physical activity involvement, which may limit them in terms of
realizing their full human potential (i.e., cognitively, physically, socially). The purpose of this dissertation was to investigate the psychosocial mechanisms as well as the sociocultural influences to understand...
Vibrio parahaemolyticus is a foodborne pathogen recognized as the leading cause of acute gastroenteritis associated with consumption of raw and undercooked seafood, particularly raw oysters, with major symptoms of nausea, vomiting, abdominal cramps and diarrhea. It is estimated that 45,000 cases of V. parahaemolyticus infection occur each year in the...
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Full Text:
nutrients and byproducts of microbial
metabolism
YanCampbell
1,2
, Mary L. Fantacone
1,2
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Though empathy has proven to be a vital component of the physician-patient relationship, recent studies have shown that medical students tend to lose empathy during their third year of medical school as they start interacting with patients for the first time. The main objective of this project was to find...
This thesis details the applications of a new method of agent-based structure synthesis. The goal of this research is to create structures that meet a structural goal within a simulated physics environment. The method proposed works as an iterative process of changing the structure, evaluating the new structure and using...