Vaccinia virus (VV) is a large DNA virus belonging to the Orthopoxvirus
family. The viral replicative life cycle takes place solely within the cytoplasm
of a mammalian host cell. The VV genome contains 196 open reading frames
which are expressed in a highly regulated and temporal fashion in order to...
Bone strength and fracture resistivity are related to a variety of factors encompassed in what is referred to as bone quality. However, bone quality is not a well-defined concept; therefore individual fracture risk cannot be predicted accurately, and osteoporosis treatment monitoring remains di cult. Clinically available imaging modalities use bone...
Lead zirconate titanate (PZT) is well known to exhibit some of the strongest piezoelectric responses, explaining why it is at the heart of piezoelectric-based microelectromechanical systems (MEMS) research. The use of pulsed laser deposition (PLD) to synthesize PZT offers many advantages over alternative deposition techniques, mainly regarding its ability to...
Prediction of colloid transport in the subsurface is relevant to researchers in a variety of fields such as contaminant transport, wastewater treatment, and bioremediation. Investigations have traditionally relied on column studies whereby mechanistic inferences must be drawn on the basis of colloid behavior at the outlet. Over the past decade,...
Atmospheric carbon reduction is arguably the most crucial facet among efforts to mitigate climate change. The Fifth International Panel of Climate Change report emphasizes a worldwide goal of maintaining global temperature elevation less than 1.5°C above pre-industrial temperatures. This report also acknowledges without the proper utilization of counteractive emission strategies...
The nonproteinogenic amino acid enduracididine is a critical component of the mannopeptimycins, cyclic glycopeptide antibiotics with activity against drug-resistant pathogens, including methicillin-resistant Staphylococcus aureus. Enduracididine is produced in Streptomyces hygroscopicus by three enzymes, MppP, MppQ, and MppR. On the basis of primary sequence analysis, MppP and MppQ are pyridoxal 5'-phosphate-dependent...