On March 24, 1999, the National Marine Fisheries Service (NMFS) published its final decision to list the Upper Willamette River evolutionarily significant unit (ESU) of chinook salmon as threatened under the Endangered Species Act (ESA). The effective date for the final listing was May 24, 1999, and the ESU is...
Five varieties of industrial hemp (Cannabis sativa) were grown in the field in Imperial Valley, CA, USA in order to determine whether light conditions or harvest times influence cannabinoid content. A total of 16 cannabinoids were investigated in this study: Delta-9-tetrahydrocannibinol (THC-d9), Delta-9-tetrahydrocannibinolic acid (THC-a), Cannabidiol (CBD), Cannabidiolic acid (CBD-a),...
Zebrafish are capable of fully regenerating organs and tissue such as their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals including humans have a greatly reduced capacity for wound healing. The ability of zebrafish to undergo this regenerative process, called...
The immune toxicity of the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), commonly referred to as dioxin, has been studied for over 35 years but only recently has the profound immune suppression induced by TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through...
In the environment, it is the unbound fraction of chemical (Cfree) which is able to diffuse across environmental interfaces and biological membranes. It is therefore Cfree which drives many important biological-environmental processes including contaminant transport, bioaccumulation and toxicity. Passive sampling devices (PSDs) offer a simplified and more accurate approach for...
Over the past decade, the business sector has come under increasing pressure to improve their environmental, safety, and health (ESH) performance. This pressure has stemmed from both external and internal sources with the organization. Public image, legislative and regulatory requirements, stakeholder awareness of environmental performance, sustainable development, and changing corporate...
Polycyclic aromatic hydrocarbons (PAHs) are present in the environment as complex mixtures with components that have diverse carcinogenic potencies and mostly unknown interactive effects. Non-additive PAH interactions have been observed in regulation of cytochrome P450 (CYP) gene expression in the CYP1 family. To better understand and predict biological effects of...
Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for...
Nanotechnologies continue to permeate a multitude of industries, with diverse applications ranging from pesticides to fuel additives. The unusual behavior of nanomaterials that drives their innovation also complicates the job of toxicologists tasked with assessing their potential environmental and public health impacts. This dissertation investigates the underlying reasons for uncertainty...
The purpose of the study is to gauge the scope of bioenergy opportunities by identifying and profiling bioenergy projects and potential projects in Oregon, and learning directly from developers the key challenges and issues this nascent sector faces. Bioenergy projects are defined as projects that would produce biofuels (ethanol and...