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  • Adapting computer science technologies to bridge critical gaps in proposed Tox21 risk assessment programs

    Creator:
    Larkin, Andrew
    Abstract:
    In 2004 the National Toxicology Program published an article describing their intent to pursue toxicology testing and risk assessment practices solely reliant on high throughput in vitro datasets and in silico modeling for dose-response assessments. Support and contributions form regulatory agencies and a significant portion of the life sciences community...
    Resource Type:
    Dissertation
    Full Text:
    a “21st century” or a “Tox21” risk assessment program. As of 2014, the envisioned program is

  • Preliminary framework for the run-ahead predictive simulation software (RAPSS)

    Creator:
    Makinson, Kevin A.
    Abstract:
    The Run-Ahead Predictive Simulation Software (RAPSS) is an architecture designed for faster-than-real-time decision support for operators of complex networks. To enable further development of the RAPSS methodology, the necessary proof of principle is illustrated in two applications: decision support for shift technical advisors in nuclear power plant control rooms (RAPSS-STA),...
    Resource Type:
    Dissertation
    Full Text:
    .......................................................................................23 2.2 Probabilistic Risk Assessment (PRA

  • "Instead of tumbleweed, we have mitigation systems" : an ethnography of toxics risk, mitigation, and advocacy in IBM's deindustrialized birthplace

    Creator:
    Little, Peter C.
    Abstract:
    This dissertation draws on ethnographic data and political ecological theory to analyze the experience of residents living in the IBM-Endicott Superfund site in Endicott, New York. Combining in-depth narratives and quantitative measures from a household survey, it highlights residents' perceptions of 1) environmental health risk, 2) risk mitigation, 3) deindustrialization...
    Resource Type:
    Dissertation
    Full Text:
    Environmental Social Movements……………………………………………….29 Risk Assessment and Perception…..…………………………………………….41