Index Catalog // ScholarsArchive@OSU

MicroRNAs control neurobehavioral development and function in zebrafish

Creator:: Tal, Tamara L., Franzosa, Jill A., Tilton, Susan C., Philbrick, Kenneth A., Iwaniec, Urszula T., Turner, Russell T., Waters, Katrina M., and Tanguay, Robert L.
Abstract:: microRNAs (miRNAs) have emerged as regulators of a broad spectrum of neurodevelopmental processes, including brain morphogenesis, neuronal differentiation, and survival. While the role of miRNAs in establishing and maintaining the developing nervous system is widely appreciated, the developmental neurobehavioral role of miRNAs has yet to be defined. Here we show...
Resource Type:: Article
Full Text:: TAL ET AL.The FASEB Journal � www.fasebj.org sponses may persist throughout the life span of

Deoxyribonucleotides as Genetic and Metabolic Regulators

Creator:: Mathews, Christopher K.
Abstract:: For more than 35 years we have known that the accuracy of DNA replication is controlled in large part by the relative concentrations of the four canonical deoxyribonucleoside 5'-triphosphates (dNTPs) at the replisome. Since this field was last reviewed, about eight years ago, there has been increased understanding of the...
Resource Type:: Article
Full Text:: Federation of American Societies for Experimental Biology Accepted Manuscript http

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures.pdf

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Full Text:: 15 the Berkeley Center for Structural Biology supported in part by the National Institutes of

The circadian clock gene period extends healthspan in aging Drosophila melanogaster

Creator:: Krishnan, Natraj, Kretzchmar, Doris, Rakshit, Kuntol, Chow, Eileen, and Giebultowicz, Jadwiga M.
Abstract:: There is increasing evidence that aging is affected by biological (circadian) clocks – the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/night cycles. Recent data suggest that disruption of the mammalian circadian clock results in accelerated aging and increased age‐related pathologies such...
Resource Type:: Article
Full Text:: dSir2 and Dmp53 interact to mediate aspects of CR-dependent

History of Entomopathogenic Nematology

Creator:: Poinar, George O., Jr. and Grewal, P. S.
Abstract:: The history of entomopathogenic nematology is briefly reviewed. Topic selections include early descriptions of members of Steinernema and Heterorhabditis, how only morphology was originally used to distinguish between the species; descriptions of the symbiotic bacteria and elucidating their role in the nematode- insect complex, including antibiotic properties, phase variants, and...
Resource Type:: Article
Full Text:: biology. Photo by G. Poinar. 158 Journal of Nematology, Volume 44, No. 2, June 2012 Bedding, R. A

Cysteine dioxygenase structures from pH 4 to 9: consistent Cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Resource Type:: Article

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures(SupplementaryInformation).pdf

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Full Text:: is weaker than that of the Cys93 Sγ, consistent with the iron having 5 decreased occupancy. We

Global agricultural intensification during climate change: a role for genomics

Creator:: Abberton, Michael, Batley, Jacqueline, Bentley, Alison, Bryant, John, Cai, Hongwei, Cockram, James, Costa de Oliveira, Antonio, Cseke, Leland J., Dempewolf, Hannes, De Pace, Ciro, Edwards, David, Gepts, Paul, Greenland, Andy, Hall, Anthony E., Henry, Robert, Hori, Kiyosumi, Howe, Glenn Thomas, Hughes, Stephen, Humphreys, Mike, Lightfoot, David, Marshall, Athole, Mayes, Sean, Nguyen, Henry T., Ogbonnaya, Francis C., Ortiz, Rodomiro, Paterson, Andrew H., Tuberosa, Roberto, Valliyodan, Babu, Varshney, Rajeev K., and Yano, Masahiro
Abstract:: Agriculture is now facing the ‘perfect storm’ of climate change, increasing costs of fertilizer and rising food demands from a larger and wealthier human population. These factors point to a global food deficit unless the efficiency and resilience of crop production is increased. The intensification of agriculture has focused on...
Resource Type:: Article
Full Text:: Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists

Darwin's Spectre: Evolutionary Biology in the Modern World (review)

Creator:: Farber, Paul Lawrence
Resource Type:: Article
Full Text:: Biology in the Modern World] Social History of Medicine 2000 Farber, Paul

Multiple steroid and thyroid hormones detected in baleen from eight whale species

Creator:: Lysiak, Nadine S., Moore, Michael J., Hunt, Kathleen E., Robbins, Jooke, Seton, Rosemary E., Buck, C. Loren, and Torres, Leigh G.
Abstract:: Recent studies have demonstrated that some hormones are present in baleen powder from bowhead (Balaena mysticetus) and North Atlantic right (Eubalaena glacialis) whales. To test the potential generalizability of this technique for studies of stress and reproduction in large whales, we sought to determine whether all major classes of steroid...
Resource Type:: Article
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ScholarsArchive@OSU

MicroRNAs control neurobehavioral development and function in zebrafish

Deoxyribonucleotides as Genetic and Metabolic Regulators

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures.pdf

The circadian clock gene period extends healthspan in aging Drosophila melanogaster

History of Entomopathogenic Nematology

Cysteine dioxygenase structures from pH 4 to 9: consistent Cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures(SupplementaryInformation).pdf

Global agricultural intensification during climate change: a role for genomics

Darwin's Spectre: Evolutionary Biology in the Modern World (review)

Multiple steroid and thyroid hormones detected in baleen from eight whale species

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