We investigated DNA methylomes of pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurred in two tracks: de novo methylation of small functional compartments and demethylation of large intercompartmental backbones. The deviations were exaggerated in lamina-associated...
Oregon Biography Index is intended to serve primarily as a starting point in locating biographies of Oregonians. We have indexed 47 historical volumes which are either entirely devoted to biographies or have large self-contained biographical sections. The profiles in the books vary widely in accuracy and detail. Birth dates of...