An experiment was conducted to determine if selection from
standardized litters would be effective in separating lines of mice
selected for increased and decreased litter weight at 14 days of age,
and if response to selection on this maternally influenced trait could
be accurately predicted.
Data were collected on litter...
The location of a lactating mouse in a cage of two compartments,
a nest area and a larger wire cage, was continuously recorded for ten
days after parturition. Three experimental groups within each of two
inbred lines, A/J and C57BL/6J, were tested: first generation,
unfostered; second generation, unfostered; and second...
Attempts were made to study the effect of parathion and DDT
on the postnatal development of mice. Parathion, DDT or corn oil
(control) was administered to gravid mice during the first, second,
and third trimesters of pregnancy. Thus, nine groups of offspring
were obtained. Four different techniques, Audiogenic Seizure,
Conditioned...
An experiment was conducted to examine the responses to
selection for high and low rate of gain in the mouse under a system
whereby inbreeding was maximized. Rate of gain was measured by an
index designed to include gains in both the pre- and postweaning
periods with the gains in...
The effect of vitamin B-6 (VB6) deficiency in mice on host
susceptibility to primary and secondary Moloney-sarcoma virus
(MSV)-induced tumor growth, cytotoxic activities of T cells,
antibodies and natural killer (NK) cells, and phagocytosis by
macrophages was examined. Five- to six-week old female C57B1/6 mice
were fed 20% casein diets...
Ulcerative dermatitis (UD) is a common condition in C57BL/6 mice that is poorly understood and challenging to treat. Inconsistently there have been reports of an increased incidence of the disease in female mice, mice exposed to certain diets, mice of advanced age, and in several seasons. These inconsistencies indicated a...