Vitamin C is an essential component of the human diet. Uptake of vitamin C in the cell is regulated by the function of sodium-dependent vitamin C transporters (SVCTs). SVCT1 (encoded by the SLC23A1 gene) is expressed in the colon, liver and kidney, where it plays a vital role in determining...
Research progress to understand the role of vitamin C (ascorbic acid) in human health has been slow in coming. This is predominantly the result of several flawed approaches to study design, often lacking a full appreciation of the redox chemistry and biology of ascorbic acid. In this review, we summarize...
Inhibiting pancreatic lipase activity is an effective means of reducing fat absorption, which may have a role in combating obesity by limiting energy intake. The use of pharmaceutical lipase inhibitors has been limited due to the prevalence of undesirable side effects. Polyphenols represent an alternative strategy to inhibit digestive enzymes...
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Michelle M. Hess, Alexander J. Michels, and Balz Frei
Linus Pauling Institute, Oregon State University
Inhibiting pancreatic lipase activity is an effective means of reducing fat absorption, which may have a role in combating obesity by limiting energy intake. The use of pharmaceutical lipase inhibitors has been limited due to the prevalence of undesirable side effects. Polyphenols represent an alternative strategy to inhibit digestive enzymes...
Full Text:
and Tea Extracts and Their Primary Catechins in vitro
Michelle M. Hess, Alexander J. Michels, and Balz
Inhibiting pancreatic lipase activity is an effective means of reducing fat absorption, which may have a role in combating obesity by limiting energy intake. The use of pharmaceutical lipase inhibitors has been limited due to the prevalence of undesirable side effects. Polyphenols represent an alternative strategy to inhibit digestive enzymes...
The Soil Conditioning Index (SCI) aids the conservationist in designing crop rotations and residue management practices when low organic matter, poor soil tilt, and crusting problems are identified. The Natural Resources and Conservation Services (NRCS) field staff and others use the SCI as a qualitative tool during conservation planning. In...
Airborne Wind Energy System (AWES) are quickly coming to fruition, with increased energy production while reducing the cost of implementation and materials. This thesis develops a new computational model for a tethered AWES and characterizes a new rapid prototyping method with the objective of supporting the design and rapid prototyping...
Aim: There is growing interest in pharmacologic ascorbate (Asc) and its therapeutic properties (Levine et al. Adv Nutr 2011;2:78). W e examined cell viability, histone deacetylase (HDAC) expression, and related protein modifications in cancer versus non- cancer colon epithelial cells following exposure to Asc.
Methods: MTT assays were conducted in...
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, p53, tubulin)
Dr. Rod Dashwood and lab (IBT)
Dr. Balz Frei, Dr. Alex Michels (LPI) Dr.
Mark