Five varieties of industrial hemp (Cannabis sativa) were grown in the field in Imperial Valley, CA, USA in order to determine whether light conditions or harvest times influence cannabinoid content. A total of 16 cannabinoids were investigated in this study: Delta-9-tetrahydrocannibinol (THC-d9), Delta-9-tetrahydrocannibinolic acid (THC-a), Cannabidiol (CBD), Cannabidiolic acid (CBD-a),...
Zebrafish are capable of fully regenerating organs and tissue such as their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals including humans have a greatly reduced capacity for wound healing. The ability of zebrafish to undergo this regenerative process, called...
The entire human population is chronically exposed to various
contaminants, including lead and chlorinated hydrocarbon pesticides.
Studies were undertaken to assess the effects of chronic exposure to
lead on the toxicities of two such pesticides, lindane and dieldrin.
Mice were given lead as the acetate in drinking water, at levels...
Pineal acetylserotonin methyltransferase (ASMT) activities
in rainbow trout were reported on by Hafeez and Quay (1971). The validity of certain
assay parameters used by these researchers
were investigated. With the exception of incubation temperature,
all parameters studied proved to be quite valid. Temperature
studies indicated a low stability for trout...
Tissue distribution studies of calcium and lead in brain tissue
of rats were increased subsequent to a single intravenous injection
of lead, 10 mg/kg, in the form of lead acetate. Time-course
studies demonstrated that brain concentrations of calcium and lead
(in terms of wet tissue weight) were found to be...
Pineal hydroxyindole-0-methyltransferase (HIOMT) activity
was monitored over a 24 h period under three different photoperiods,
16L:8D, 8L: 16D, and 12 L:12D. It was observed that in all three
groups of fish HIOMT activity was high' during the dark portion of the
photoperiod in comparison to activity during the light portion....
Polycyclic aromatic hydrocarbons (PAHs) are present in the environment as complex mixtures with components that have diverse carcinogenic potencies and mostly unknown interactive effects. Non-additive PAH interactions have been observed in regulation of cytochrome P450 (CYP) gene expression in the CYP1 family. To better understand and predict biological effects of...