Leukemogenesis, uncontrolled proliferation of dysfunctional, transformed immature lymphocytes, appears, especially in children, to be associated with abrogation of normal lymphopoiesis, and thymopoiesis in the case of T cell leukemias. Sequence specific transcription factors (SSTFs) are nuclear control switches that respond to cellular signals to alter cell state and cell fate...
This bulletin is one of a series on organic potato production developed by “OSPUD.” OSPUD is a collaboration among Oregon State University personnel and 11 farmers operating diversified organic vegetable farms. The purpose of OSPUD is to improve potato quality and profitability through a participatory learning process and on-farm, farmer-directed...
This qualitative study considered faith as a part of the lifespan development of adults with developmental disabilities between the ages of 30 and 67 years. Ten individuals who participated attended an adapted liturgy and/or fellowship group hosted by two Roman Catholic faith formation groups. The data were gathered through individual,...
BCL11B, a gene regulatory transcription factor, is known to be a regulator of T cell development in the immune system, and has been identified as a tumor suppressor for T cell leukemias. Defining the molecular events that regulate the activity of BCL11B will provide potential drug targets that will aid...
Controversy regarding moral development research has given rise to a proliferation of theories competing for acceptance. For all these researchers, the work of Lawrence Kohlberg is the pivot point for comparisons, contrasts, and discussions. Still, no theories to date adequately describe and document a theoretically complete conception of moral judgment...
It is well known that in mice the extension in lifespan by rapamycin is sexually dimorphic, in that it has a larger effect in females than males. In a previous study we showed that in male C57BL6 mice, rapamycin had less profound effects in both gene expression and liver metabolites...
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that rapamycin acts as a
dietary restriction mimetic (Selman et al. 2009). Further-
more, when
The purpose of this study was to identify the knowledge, attitudes, practices and barriers related to handwashing in the restaurant environment. The study was designed with multidimensional study tools to include: a focus group conversation with questions to food workers to develop an initial understanding of knowledge, practice and attitudes...
Thymocytes, cells of the thymus gland, undergo developmental steps that
enable them to properly mature into T-cells. Errors in gene expression may lead to
improper maturation and potentially mass proliferation of dysfunctional thymocytes,
a hallmark of leukemia or lymphoma. BCL11B is a tumor suppressor and
transcriptional regulatory protein that is...
Sexual maturation and sex differentiation comprise facets of a
common theme: reproduction. The endocrine system regulates many
of the critical physiological processes necessary for reproduction and
offers a framework within which technologies can be developed for
controlling sexual maturation and sex differentiation. The studies
described in this thesis were undertaken...