This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Hindawi Publishing Corporation. The published article can be found at: http://dx.doi.org/10.1155/2015/169256
Objective:
To evaluate the effect of Nelumbo Nucifera leaf water extract (NNLE) on insulinoma (RIN) cells induced by interleukin-1ß (IL-1ß) and interfer-on-g (IFN-γ), and injured pancreatic ß-cells induced by Streptozotocin (STZ) in rats.
Methods:
The anti-oxidative effects of NNLE were assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and nitric oxide (NO) scavenging assays....
BACKGROUND: Glucose homeostasis is distorted by defects of the PI3K/AKT and AMPK pathways in insulin-sensitive tissues, allowing the accumulation of glucose in the blood. The purpose of this study was to assess the effects and mechanisms by which ethanol extract of Caulerpa lentillifera (CLE) regulates glucose metabolism in C57BL/KsJ-db/db (db/db)...
The variability introduced into measurements by a measuring instrument is referred to as measurement instrument precision. Experimental procedures and analysis methods exist when measurements are repeatable and can be repeated on the same item. However, when the measurements are destructive and repeated measurements are not possible, estimating measuring instrument precision...
Desalination stands for removing salt from saline water, and produce freshwater. Desalination technologies have been envisioned as a potential solution for freshwater production from oceans as an immense source of water acquiring 97% earth’s water, and 75% of earth’s surface. However, one third of world’s population face water scarcity every...
Background: Pearl millet [Pennisetum glaucum (L.) R. Br.] is a widely cultivated drought-and high-temperature tolerant C4 cereal grown under dryland, rainfed and irrigated conditions in drought-prone regions of the tropics and sub-tropics of Africa, South Asia and the Americas. It is considered an orphan crop with relatively few genomic and...
Mukti Ashram is a rehabilitation center in north India that works with ex-child laborer boys. Fieldwork completed at the ashram in 1997-98 centered around the issue of the organization's attempt to enact social change through the engineering of community within the ashram's walls. Several fundamental processes that contribute to this...
Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials,
but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme
metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...
In rodent models as well as in fish models there are significant
species differences in the susceptibility toward aflatoxin B₁ (AFB₁)
carcinogenesis. Mouse is less susceptible toward AFB₁ carcinogenesis
than rat. Researchers have come to the conclusion that the lower
susceptibility of mice is not a result of less effective...
Indole-3-carbinol (I3C) inhibits chemically induced tumor
formation in rodents and rainbow trout. This study examines the
effect of I3C and its analog, indole-3-acetonitrile (I3N) on
xenobiotic-metabolizing enzyme systems. The modulation of these enzyme
systems have been shown to have significant effects on the
interaction of chemical carcinogens and cellular constituents....