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  • In Vitro Evaluation of Therapeutic Laser Treatment on Equine Tendon Fibroblasts

    Creator:
    Husby, Kirsty A.
    Abstract:
    Previous investigations have failed to show benefits of low level laser therapy (LLLT) for tendon healing in horses, contrary to reports in other species. We hypothesized that delivery of LLLT at manufacturer-recommended energy fluence through equine cadaver skin to equine tendon-derived fibroblasts in vitro would increase cell proliferation, metabolic activity...
    Resource Type:
    Masters Thesis
    Full Text:
    like to thank the other members of my graduate committee, Dr. Stacy Semevolos, Dr. Oleh Taratula

  • Continuous microwave extraction of peppermint oil

    Creator:
    Smith, Connor J.
    Abstract:
    Steam distillation has been the common method of extraction of essential oils from plants for more than a century. The use of microwave energy has been suggested as an alternative distillation method that would: reduce water usage, dependence on non-renewable energy sources, and the carbon footprint. A byproduct of this...
    Resource Type:
    Masters Thesis

  • Membrane permeability properties of human granulocytes

    Creator:
    Vian, Alexander M.
    Abstract:
    In the last decade, there has been renewed interest in the use of granulocyte transfusions to treat infections in individuals with compromised immune systems. However, granulocytes only remain functional for about a day after isolation and this short shelf life is a significant drawback. Cryopreservation would allow long term storage...
    Resource Type:
    Masters Thesis

  • Non-viral Vectors for Ocular Gene Delivery

    Creator:
    Herrera-Barerra, Marco, F.
    Abstract:
    Nucleic acid therapeutics has cemented itself as one of the most efficacious and robust avenues for treatment of a wide range of diseases from vaccine development to treatment of liver, retina, cancer applications. Non-viral mediated gene delivery using lipid-based nanoparticle (LNP) carriers has proven its compatibility with addressing unexpected, fast...
    Resource Type:
    Dissertation
    Full Text:
    . Oleh Taratula and Dr. Conroy Sun provided input during for manuscript finalization. Dr. Gaurav

  • Magnetic Properties of Polymer Nanocomposite Materials Prepared using Multi Jet Fusion 3D Printing Methods

    Creator:
    Cannamela, Madeleine G.
    Abstract:
    The goal of this research was to explore if an inkjet 3D printing technology, known as Multi Jet Fusion (MJF), could be used to fabricate magnetic polymer nanocomposites with systematically varied volume fractions of magnetic nanoparticles. Soft magnetic nanoparticles were chosen because of their applications in communications technologies and other...
    Resource Type:
    Masters Thesis
    Full Text:
    Dr. Oleh Taratula, Dr. Skip Rochefort, Dr. Megumi Kawasaki and Dr. Vrushali Bokil for your time

  • Transdermal Delivery of Atenolol to Cats

    Creator:
    Mohamed, Sumeia M.
    Abstract:
    This thesis describes in-vitro and in-vivo evaluation of a transdermal atenolol formulation developed at Oregon State University, College of Pharmacy. The formulation was prepared from carbomer as a gel base with propylene glycol, glycerol, ethanol, polysorbate 80 and dimethyl-isosorbide (DMI) as mixture of penetration enhancing agents. The effect of the...
    Resource Type:
    Dissertation
    Full Text:
    thesis committee: Dr Oleh Taratula, Dr. Gaurav Sahay and Dr. Sun Conroy for their encouragement

  • Application of Bootstrap Methods in Bioequivalence Studies for Oral Generic Prodrug Products

    Creator:
    Li, Wenjing
    Abstract:
    The methodology to perform bioequivalence studies for prodrug products has not been finalized by FDA leaving the investigators to speculate over the proper approach. This study innovatively utilized the bootstrap methods for testing in vivo bioequivalence on both parent drug and metabolite of four prodrug products: Clopidogrel, Prednisone, Allopurinol, and...
    Resource Type:
    Dissertation
    Full Text:
    . committee: Adam Alani, Ph.D.; Harold Bae, Ph.D.; Oleh Taratula, Ph.D.; and Lan Xue, Ph.D.. Without their

  • Development of thermosensitive injectable hydrogel and transdermal controlled release formulations for Tacrolimus

    Creator:
    Nguyen, Duc X.
    Abstract:
    TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...
    Resource Type:
    Dissertation
    Full Text:
    many other works. I would like to thank my committee members Dr. Mark Christensen, Dr. Oleh Taratula

  • Pharmacokinetics of Flunixin in Elephants, Cefovecin in African Lions, and Gamithromycin in Alpacas

    Creator:
    Alshahrani, Sultan M.
    Abstract:
    Foot pathology is a real problem in captive elephants. Osteoarthritis is the major concern among musculoskeletal disorders and foot health problems for elephants in North America zoos with one-­‐half of Elephants in captivity showing foot health care problems in zoos. A higher ratio of captive Asian elephants (Elephas maximus) is...
    Resource Type:
    Dissertation
    Full Text:
      committee  members   Dr.   Adam  Alani,   Dr.   Oleh   Taratula,   and   Dr.   Conroy

  • Role of Melanocytic Vitamin D Receptor (VDR) in UVB-induced Melanocyte Homeostasisand Keratinocytic Retinoid–X-Receptor α (RXRα) in UVB Induced Melanomagenesis

    Creator:
    Chagani, Sharmeen
    Abstract:
    Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...
    Resource Type:
    Dissertation