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The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on acetyl-CoA carboxylase and other lipogenic enzymes

Creator:: McKim, James M.
Resource Type:: Dissertation
Full Text:: . for the degree of Doctor of Philosophy in Toxicology presented on April 14, 1989 Title: The Effects

Characterization of pyruvate carboxylase responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in C57BL/6J male Ah[superscript d/d] mice

Creator:: Ryu, Byung-Woo
Resource Type:: Dissertation
Full Text:: THE THESIS OF Byung-Woo Ryu for the degree of Doctor of Philosophy in Toxicology presented on

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: in Toxicology presented on July 2S, 1999. Title: The Effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

Creator:: Huang, Wentian
Resource Type:: Dissertation
Full Text:: Doctor of Philosophy in Toxicology presented on June 26 1997. Title: Effect of 2,3,7,8

Regulation of hepatic pyruvate carboxylase in 2,3,7,8-Tetrachlorodibenzo-p-dioxin treated C57BL/6J mice and their pair-fed controls

Creator:: Roy, Shukla
Resource Type:: Dissertation
Full Text:: Roy for the degree of Doctor of Philosophy in Toxicology presented on September 10, 1998. Title

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Toxicology presented on May 1. 2006. Title: The Influence of Aryl

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Creator:: Marshall, Nikki B.
Abstract:: The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Resource Type:: Dissertation

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Creator:: Rohlman, Diana
Abstract:: The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
Resource Type:: Dissertation
Full Text:: for the degree of Doctor of Philosophy in Toxicology presented on May 15, 2013. Title

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

Creator:: Sparrow, Barney R.
Abstract:: The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male mice. A dose-dependent reduction of PC levels and activity occurred in animals given a single intraperitoneal dose of TCDD in a corn oil carrier. The dose ranged from 1 to...
Resource Type:: Dissertation
Full Text:: OF THE THESIS OF Barney R. Sparrow for the degree of Doctor of Philosophy in Toxicology presented

ScholarsArchive@OSU

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on acetyl-CoA carboxylase and other lipogenic enzymes

Characterization of pyruvate carboxylase responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in C57BL/6J male Ah[superscript d/d] mice

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

Regulation of hepatic pyruvate carboxylase in 2,3,7,8-Tetrachlorodibenzo-p-dioxin treated C57BL/6J mice and their pair-fed controls

The influence of aryl hydrocarbon receptor activation on T cell fate

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

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