2 -acetylaminofluorene -induced hepatocarcinogenesis in rats
proceeds in stages of initiation and promotion, similar to experimental
systems, in mouse skin. In this study promoters of liver
tumorigenesis, phenobarbital, DDT and butylated hydroxytoluene
(BHT), were compared to non-promoters, amobarbital, diphenylhydantoin
(DPH) and benz(a)anthracene (BA), for their ability to
cause liver growth...
Hydrocarbon solvents are widely used in the production of paints, adhesives, dyes, polymers, plastics, textiles, printing inks, agricultural products and pharmaceuticals. While the neuropathic potential of aliphatic solvents was shown in the 1970s, little is known about the neuropathic potential of aromatic solvents. The present study examines such solvents, 1,2-diethylbenzene...
This study was designed to assess chiorpyrifos exposure of a group of farmers by determining internal dose associated with a given application of this insecticide. This involved the monitoring of urinary levels of 3,5,6 trichloro-2-pyridinol (TCP), the major metabolite of chlorpyrifos. Incidental exposure was evaluated by determining the levels of...
In 1993 The Oregon Department of Environmental Quality developed a Cross-media Comparative Risk Assessment model to address certain regulatory concerns. Due to budget constraints the model was never beta tested. Now in 1995, the X-media project has been reopened, and the model revised, and tested. Specific revisions include: 1) Upgrade...
Developing steelhead trout eggs and sac fry were examined for
wet, dry and lipid weights and for fatty acid composition over the
period from fertilization until the disappearance of the yolk sac, 69
days after fertilization. The yolk sac and embryo or fry were
separated shortly before hatching, and the...
The herbicide, Dacthal (dimethyl 2,3,5,6,-tetrachloroterephthalate) is
hydrolyzed to give the corresponding diacid and this derivative is a common
contaminant in ground water. In the Ontario region of eastern Oregon the
use of this herbicide on onions has resulted in the contamination of an
aquifer with this derivative. Since movement to...