Bovine respiratory disease complex (BRD) is an infection of both the upper and lower respiratory tract and includes components of rhinitis, otitis, tracheitis, and pneumonia. Bovine respiratory disease (BRD) is one of the most common causes of morbidity and mortality of calves in the United States and world-wide. Besides the...
The effects of alfaxalone (A-HPCD), propofol (P), ketamine-diazepam (KD) and tiletamine-zolazepam (TZ) administered IV in dogs on cardiovascular and respiratory systems, acid-base balance and electrolytes have been reported in the literature, but a study that compares IV TZ to the other induction protocols (IP) is needed. Six dogs enrolled in...
Pulmonic stenosis (PS) is one of the most commonly encountered congenital cardiac defects in canine patients. English bulldogs have an increased risk of PS as compared to other dog breeds and have a higher reported prevalence of type II/type B/dysplastic pulmonic valve morphology. It has been shown that the dysplastic...
Corneal ulcers are one of the most common eye conditions of the horse, with potentially serious complications such as loss of vision or the eye itself. They are extremely painful due to the large number of sensory nerve endings found in the cornea. Horses frequently show signs of ophthalmic pain...
Previous investigations have failed to show benefits of low level laser therapy (LLLT) for tendon healing in horses, contrary to reports in other species. We hypothesized that delivery of LLLT at manufacturer-recommended energy fluence through equine cadaver skin to equine tendon-derived fibroblasts in vitro would increase cell proliferation, metabolic activity...
Feline injection site sarcomas (FISS) are frequently encountered cutaneous and subcutaneous neoplasms of cats. Significant patient morbidity is related to the invasiveness these tumors display, typically requiring extensive local excision or amputation. As with many veterinary tumors, survival time and tumor recurrence for FISS is highly influenced by histologic margin...
Prenatal exposure to excess androgens, testosterone in particular, has clear effects on potential ram fertility. Utilizing breeding soundness examinations in male sheep will assess the ram's potential ability to impregnate a certain number of healthy females during a defined breeding season. Identifying rams that have high breeding potential can provide...
Ulcerative dermatitis (UD) is a common condition in C57BL/6 mice that is poorly understood and challenging to treat. Inconsistently there have been reports of an increased incidence of the disease in female mice, mice exposed to certain diets, mice of advanced age, and in several seasons. These inconsistencies indicated a...
Background
Bcl11b, previously CTIP2, is a zinc finger nuclear transcription factor involved in the development of keratinocytes, teeth, T lymphocytes, and nervous tissue. Expression of Bcl11b has been reported in human head and neck squamous cell carcinoma (HNSCC) and increased expression correlates with poorly differentiated tumors. This study aimed to...
Linear M-mode (1D) and later 2-dimensional (2D) measurements of the left atrium (LA) are commonly been used to assess LA size in veterinary studies despite the fact that studies in human subjects have shown that LA volume (LAV) more accurately reflects LA size than linear measurements due to the complex...