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  • Functional analysis of novel β-catenin mutants

    Creator:
    Al-Fageeh, Mohamed B.
    Abstract:
    β-catenin is a multi functional protein that is involved in cell-cell adhesion and cell signaling. In non-stimulated cells, β-catenin is tightly down-regulated by GSK-3β-dependent phosphorylation at Ser and Thr residues, followed by rapid ubiquitination and proteasomal degradation. It is well established that mutations within the regulatory GSK-3β region lead to...
    Resource Type:
    Masters Thesis
    Full Text:
    would like to thank Dr. Andrew Buermeyer, Dr.Chrissa Kioussi and Dr. Jeffrey Widrick for being on my

  • Small RNA pathways in plants

    Creator:
    Montgomery, Taiowa A.
    Abstract:
    miRNA-guided cleavage initiates entry of primary transcripts into the trans-acting siRNA (tasiRNA) biogenesis pathway involving RNA-DEPENDENT RNA POLYMERASE6 (RDR6), DICER-LIKE 4 (DCL4), and SUPPRESSOR OF GENE SILENCING3 (SGS3). Arabidopsis thaliana TAS1 and TAS2 families yield tasiRNA that form through miR173- guided initiation cleavage on the 5’ side of the siRNA-generating...
    Resource Type:
    Dissertation

  • A comparision of substrate utilization during exercise among males and females varying in age and training status

    Creator:
    Onsiri, Sombat
    Abstract:
    Exercise training has consistently been shown to increase fat utilization during exercise, while conflicting results have been reported on the effects of sex and age on fuel metabolism during exercise. PURPOSE: The primary objective of this investigation was to compare fat and carbohydrate utilization during exercise among males and females...
    Resource Type:
    Dissertation
    Full Text:
    shared his thought and knowledge for my study and my dissertation; Dr. Jeff Widrick, my committee

  • Purification and characterization of recombinant calpain-5

    Creator:
    Wang, Mei-Chuan
    Abstract:
    Recombinant human calpain-5 was expressed in insect cells using a baculovirus system. The expressed calpain-5 was purified by both traditional chromatography and by affinity-column chromatography. Both methods yielded active protease. Calpain-5 displayed very limited hydrophobicity. This indicated that calpain-5 is not a membrane binding protein. Calpain-5 had pI of 8.3....
    Resource Type:
    Dissertation
    Full Text:
    allowing me to use his lab equipment; Dr. Jeff Widrick for friendly talk and sharing of antibodies; and Dr

  • Bone gains in adolescent athletes and non-athletes

    Creator:
    Rinder, Todd Anthony
    Abstract:
    Discordance in bone mass between young adult swimmers and soccer players may be a direct result of differences in bone loading patterns that influence bone mineralization during growth. Our aim was to evaluate whether sports participation (soccer and swimming) had an independent effect on bone mass accrual at the hip...
    Resource Type:
    Dissertation
    Full Text:
    like to thank the members of my committeeRod Harter, Jeff Widrick, Tom Roberts, and Luana Beeson for

  • Do running and fatigued running relate to tibial stress fractures?

    Creator:
    Sasimontonkul, Siriporn
    Abstract:
    Tibial stress fractures are common in runners. However, it is unclear what factors are associated with tibial stress fractures. This study aimed to investigate 1) magnitudes of bone contact forces occurring while running 2) whether or not repeated application of running loads is sufficient to explain tibial stress fractures and...
    Resource Type:
    Dissertation
    Full Text:
    Bay, Dr. Mike Pavol, Dr. Michael Schuyler, Dr. Rod Harter, Dr. Jeff Widrick and Dr. Marjorie Reed

  • Multiple stressors and amphibian population declines

    Creator:
    Hatch, Audrey C.
    Abstract:
    In the past decade, declines in amphibian populations have captured scientific and popular interest. The causes of the declines are likely to be complex and involve interactions between several environmental stressors. Using multifactorial experiments, I investigated the combined effects of several anthropogenic stressors on developing amphibians in Oregon, USA. In...
    Resource Type:
    Dissertation
    Full Text:
    Jepson, Bob Mason and my Graduate Representative Jeff Widrick have all provided support and assistance

  • Validity and reliability analysis of Cooper's 12-minute run and the multistage shuttle run in healthy adults

    Creator:
    Penry, Jason T.
    Abstract:
    Field tests are often the most practical method to assess aerobic fitness, but demonstrate greater error variability than laboratory tests. Researchers can improve field tests by identifying factors that contribute to systematic error in VO₂max estimation. PURPOSE: To examine the validity and reliability evidence of two field tests of aerobic...
    Resource Type:
    Dissertation
    Full Text:
    and mentorship. – Dr. Joonkoo Yun, Dr. Melinda Manore, Dr. Jeff Widrick, and Dr. Dwaine Plaza

  • The effects of whole body vibration on the neuromuscular system

    Creator:
    Hong, Junggi
    Abstract:
    Recently, changes in human performance following whole-body vibration (WBV) training have been attributed to enhanced neuromuscular function. However, the exact neural and muscular mechanisms responsible for these changes remain less understood. The purpose of this study was to evaluate the acute and chronic effects of whole body vibration on the...
    Resource Type:
    Dissertation

  • Nutritional characteristics of dormant season grazing within a winterfat (Krascheninnikovia lanata (Gueldenstaedt)) dominated plant community, and the effect of seedbed preparation on the emergence and survival of winterfat and squirreltail (Elymus elymoides (Raf.) Swezey) seedlings

    Creator:
    Estes, Mark G.
    Abstract:
    The effect of seedbed preparation on the emergence and survival of winterfat (Krascheninnikovia lanata (Gueldenstaedt)) and squirreltail (Elymus elymoides (Raf.) Swezey)) seedlings was determined, while quantifying nutritional changes through the dormant season for four range species. In November of 2004 twenty 9m x 8m plots were randomly prepared with one...
    Resource Type:
    Masters Thesis