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Browsing by Author "Giebultowicz, Jadwiga M."

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Browsing by Author "Giebultowicz, Jadwiga M."

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  • The circadian clock gene period extends healthspan in aging Drosophila melanogaster 
    Krishnan, Natraj; Kretzchmar, Doris; Rakshit, Kuntol; Chow, Eileen; Giebultowicz, Jadwiga M. (Impact Journals, 2009-11-19)
    There is increasing evidence that aging is affected by biological (circadian) clocks – the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/nigh ...
  • Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster 
    Beaver, Laura M.; Klichko, Vladimir I.; Chow, Eileen S.; Kotwica-Rolinska, Joanna; Williamson, Marisa; Orr, William C.; Radyuk, Svetlana N.; Giebultowicz, Jadwiga M. (Public Library of Science, 2012-11-30)
    Circadian clocks generate daily rhythms in neuronal, physiological, and metabolic functions. Previous studies in mammals reported daily fluctuations in levels of the major endogenous antioxidant, glutathione (GSH), but t ...
  • Effects of Aging on the Molecular Circadian Oscillations in Drosophila 
    Rakshit, Kuntol; Krishnan, Natraj; Guzik, Elzbieta M.; Pyza, Elzbieta; Giebultowicz, Jadwiga M. (Informa Healthcare USA, Inc., 2012-02)
    Circadian clocks maintain temporal homeostasis by generating daily output rhythms in molecular, cellular, and physiological functions. Output rhythms, such as sleep/wake cycles and hormonal fluctuations, tend to deterior ...
  • Involvement of circadian clock genes in reproduction of Drosophila melanogaster 
    Beaver, Laura M. (2002-12-10)
    Daily (circadian) rhythms exist at molecular, physiological, and behavioral levels and coordinate many life functions. This coordination is believed to contribute to an organism's fitness, however, such contributions h ...
  • Loss of circadian clock accelerates aging in neurodegeneration-prone mutants 
    Krishnan, Natraj; Rakshit, Kuntol; Chow, Eileen S.; Wentzell, Jill S.; Kretzschmar, Doris; Giebultowicz, Jadwiga M. (Elsevier, 2011-12-18)
    Circadian clocks generate rhythms in molecular, cellular, physiological, and behavioral processes. Recent studies suggest that disruption of the clock mechanism accelerates organismal senescence and age-related patholo ...
  • Oxidative Stress Response Genes: A Circadian Connection? 
    McAllister, Marisa C. (2010-08-13)
    Circadian clocks are internal mechanisms regulating many physiological processes. Research suggests that the circadian clock may regulate repair of cellular damage caused by reactive oxygen species (ROS), but molecular ...
  • You can’t beat the clock : oxidative stress and period mutants in Drosophila melanogaster 
    Davis, Andrew J. (2007-11-01)
    The free-radical theory of aging proposes that intracellular accumulation of oxidative damage caused by reactive oxygen species (ROS) is responsible for the process of senescence. ROS are produced during normal aerobic ...

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