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Browsing by Author "Givan, Scott A."

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Browsing by Author "Givan, Scott A."

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  • Computational and analytical framework for small RNA profiling by high-throughput sequencing 
    Fahlgren, Noah; Sullivan, Christopher M.; Kasschau, Krisitin D.; Chapman, Elisabeth J.; Cumbie, Jason S.; Montgomery, Taiowa A.; Gilbert, Sunny D.; Dasenko, Mark; Backman, Tyler W. H.; Givan, Scott A.; Carrington, James C. (Cold Spring Harbor Laboratory Press, 2009-05)
    The advent of high-throughput sequencing (HTS) methods has enabled direct approaches to quantitatively profile small RNA populations. However, these methods have been limited by several factors, including representation ...
  • Conserved properties in the metagenome of a large bacterioplankton population 
    Wilhelm, Larry John (2007-04-03)
    Candidatus Pelagibacter ubique is the first cultured representative of the SAR11 clade, a clade that is found throughout the oceans and accounts for approximately 25% of all bacterial cells [1]. It has a streamlined gen ...
  • Genome-Wide Profiling and Analysis of Arabidopsis siRNAs 
    Kasschau, Kristin D.; Fahlgren, Noah; Chapman, Elisabeth J.; Sullivan, Christopher M.; Cumbie, Jason S.; Givan, Scott A.; Carrington, James C. (PLoS ONE, 2007-03)
    Eukaryotes contain a diversified set of small RNA-guided pathways that control genes, repeated sequences, and viruses at the transcriptional and posttranscriptional levels. Genome-wide profiles and analyses of small RNA ...
  • High-Throughput Sequencing of Arabidopsis microRNAs : Evidence for Frequent Birth and Death of MIRNA Genes 
    Fahlgren, Noah; Howell, Miya D.; Kasschau, Kristin D.; Sullivan, Christopher M.; Cumbie, Jason S.; Givan, Scott A.; Law, Theresa F.; Grant, Sarah R.; Dangl, Jeffrey L.; Carrington, James C. (PLoS ONE, 2007-02)
    In plants, microRNAs (miRNAs) comprise one of two classes of small RNAs that function primarily as negative regulators at the posttranscriptional level. Several MIRNA genes in the plant kingdom are ancient, with conserv ...
  • The Personal Sequence Database: a suite of tools to create and maintain web-accessible sequence databases 
    Givan, Scott A.; Sullivan, Christopher M.; Carrington, James C. (BioMed Central, 2007-12-18)
    Background: Large molecular sequence databases are fundamental resources for modern bioscientists. Whether for project-specific purposes or sharing data with colleagues, it is often advantageous to maintain smaller seq ...

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