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Browsing by Subject "Marine pharmacology"
Now showing items 1-10 of 10
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(1997-10-13)My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic ...
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([S.l. : s.n.], 2002-08)Discussed herein is the evolution of the strategies for the synthesis of the ABCD ring system of the novel marine toxin azaspiracid-1. Additionally, the methods utilized for the attachment of the C1-C4 side chain, the E- ...
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(2001-10-10)This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of a ...
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(1997-05-29)
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(1996-09-13)Marine algae have been recognized as a rich resource of new and unusual organic molecules with diverse biological properties. The current need to develop new antifungal, anticancer, antibiotic and antiviral drugs has ...
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(2001-06-29)This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngby ...
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([S.l. : s.n.], 2004)A synthetic approach to the C₁-C₂₀ portion of the initially proposed structure of Azaspiracid 1 is described. The monoanomeric bisspiroketal configuration is controlled via a metal chelate between the C₉ hydroxyl and the ...
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([S.l. : s.n.], 2005-06)A synthesis plan for the marine toxin azaspiracid-1 is presented. Disconnection at the C₂₀-C₂₁ bond breaks the molecule into two halves: the C₁-C₂₀ fragment (ABCD-ring domain) and the C₂₁-C₄₀ fragment (EFGHI-ring domain) ...
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(2006-08-24)The 3-substituded indolic enamide moiety has been found in many marine compounds over the past 20 years. These indolic enamides exhibit various biological properties such as cytotoxic, anthelmintic, antimicrobial and HW- ...
Now showing items 1-10 of 10
