This is the first study to explore the ability of an enzyme to recognize and repair spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM) is known to ...

Methodologies that detect biologically active substances have important potential applications for medical diagnostics, drug discovery, and chemical and biological anti-terrorism efforts. The wide spectrum of potential ...

Every cell is faced continuously with the task of transducing a vast number of external signals into appropriate intracellular responses. In mammalian cells, membrane bound receptors modulate the production of secondar ...