Browsing by Author "Tripathy, Sasmita"

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Elovl5 Regulates the mTORC2-Akt-FOXO1 Pathway by Controlling Hepatic cis-Vaccenic Acid Synthesis in Diet-Induced Obese Mice

Tripathy, Sasmita; Jump, Donald B. (American Society for Biochemistry and Molecular Biology, 2013-01)

Elevated hepatic expression of fatty acid elongase-5 (Elovl5) induces FoxO1 phosphorylation, lowers FoxO1 nuclear content and suppresses expression of genes involved in gluconeogenesis. In this report we define the mol ...
Omega-3 Fatty Acid Supplementation and Cardiovascular Disease

Jump, Donald B.; Depner, Christopher M.; Tripathy, Sasmita (American Society for Biochemistry and Molecular Biology, 2012-12)

Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies have established an inverse relationship between the ingestion of omega-3 fatty acids [C₂₀₋₂₂ ω3 polyunsaturated fatty acids (PUFA)], ...
Polyunsaturated fatty acid synthesis and type 2 diabetes complications

Tripathy, Sasmita (2012-07-11)

Type 2 diabetes mellitus (T2DM) is a disease of multi-complications affecting more than 20 million US adults. Hyperglycemia is the classic clinical feature of diabetes, and uncontrolled hyperglycemia leads to deadly hea ...

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