There is increasing evidence that aging is affected by biological (circadian) clocks – the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/nigh ...
Beaver, Laura M.; Klichko, Vladimir I.; Chow, Eileen S.; Kotwica-Rolinska, Joanna; Williamson, Marisa; Orr, William C.; Radyuk, Svetlana N.; Giebultowicz, Jadwiga M.(Public Library of Science, 2012-11-30)
Circadian clocks generate daily rhythms in neuronal, physiological, and metabolic functions. Previous studies in mammals reported daily fluctuations in levels of the major endogenous antioxidant, glutathione (GSH), but t ...
Rakshit, Kuntol; Krishnan, Natraj; Guzik, Elzbieta M.; Pyza, Elzbieta; Giebultowicz, Jadwiga M.(Informa Healthcare USA, Inc., 2012-02)
Circadian clocks maintain temporal homeostasis by generating daily output rhythms in molecular, cellular, and physiological functions. Output rhythms, such as sleep/wake cycles and hormonal fluctuations, tend to deterior ...
Circadian clocks generate rhythms in molecular, cellular, physiological, and behavioral
processes. Recent studies suggest that disruption of the clock mechanism accelerates organismal
senescence and age-related patholo ...
