Browsing Faculty Research Publications (Zoology) by Author "Rakshit, Kuntol"

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The circadian clock gene period extends healthspan in aging Drosophila melanogaster

Krishnan, Natraj; Kretzchmar, Doris; Rakshit, Kuntol; Chow, Eileen; Giebultowicz, Jadwiga M. (Impact Journals, 2009-11-19)

There is increasing evidence that aging is affected by biological (circadian) clocks – the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/nigh ...
Effects of Aging on the Molecular Circadian Oscillations in Drosophila

Rakshit, Kuntol; Krishnan, Natraj; Guzik, Elzbieta M.; Pyza, Elzbieta; Giebultowicz, Jadwiga M. (Informa Healthcare USA, Inc., 2012-02)

Circadian clocks maintain temporal homeostasis by generating daily output rhythms in molecular, cellular, and physiological functions. Output rhythms, such as sleep/wake cycles and hormonal fluctuations, tend to deterior ...
Loss of circadian clock accelerates aging in neurodegeneration-prone mutants

Krishnan, Natraj; Rakshit, Kuntol; Chow, Eileen S.; Wentzell, Jill S.; Kretzschmar, Doris; Giebultowicz, Jadwiga M. (Elsevier, 2011-12-18)

Circadian clocks generate rhythms in molecular, cellular, physiological, and behavioral processes. Recent studies suggest that disruption of the clock mechanism accelerates organismal senescence and age-related patholo ...